التفاصيل البيبلوغرافية
العنوان: |
[Chronic renal allograft rejection. Part 2. Therapeutic possibilities] . |
عنوان ترانسليتريتد: |
Chronická rejekce renálního allostĕpu. Cást 2. Terapeutické moznosti. |
المؤلفون: |
Viklický O; Klinika nefrologie-Transplantacní centrum IKEM, Praha., Matl I, Lácha J, Muller V, Szabo A, Heemann UW |
المصدر: |
Casopis lekaru ceskych [Cas Lek Cesk] 2000 Aug 30; Vol. 139 (17), pp. 524-8. |
نوع المنشور: |
English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review |
اللغة: |
Czech |
بيانات الدورية: |
Publisher: Ceskoslovenska Lekarska Spolecnost Country of Publication: Czech Republic NLM ID: 0004743 Publication Model: Print Cited Medium: Print ISSN: 0008-7335 (Print) Linking ISSN: 00087335 NLM ISO Abbreviation: Cas Lek Cesk Subsets: MEDLINE |
أسماء مطبوعة: |
Original Publication: Praha : Ceskoslovenska Lekarska Spolecnost |
مواضيع طبية MeSH: |
Kidney Transplantation*, Graft Rejection/*therapy, Chronic Disease ; Genetic Therapy ; Graft Rejection/etiology ; Humans ; Immunosuppressive Agents/therapeutic use |
مستخلص: |
Chronic rejection represents an important cause of renal allograft loss in the long term follow up. New insights into etiopathogenesis of the chronic rejection offer possibilities for experimental therapy. Novel immunosuppressants, such as mycophenolic acid, tacrolimus or rapamycin as well as lipid lowering drugs, angiotensin-converting enzyme inhibitors or AT-1 receptor blockers, may reduce of effects the risk factors on the progression of chronic rejection. In the future, gene therapy may offer additional possibilities to prevent chronic rejection. This review deals with possibilities of prevention of the chronic renal allograft rejection based on experimental evidences and current therapeutic concepts and puts these options into a rational perspective. |
Number of References: |
39 |
المشرفين على المادة: |
0 (Immunosuppressive Agents) |
تواريخ الأحداث: |
Date Created: 20001208 Date Completed: 20010104 Latest Revision: 20121115 |
رمز التحديث: |
20240627 |
PMID: |
11109284 |
قاعدة البيانات: |
MEDLINE |