دورية أكاديمية
[Water-exchange processes in hyaline cartilage and its basic components in a normal state and in osteoarthritis].
| العنوان: | [Water-exchange processes in hyaline cartilage and its basic components in a normal state and in osteoarthritis]. |
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| عنوان ترانسليتريتد: | Vlagoobmennye protsessy v gialinovom khriashche i ego osnovnykh komponentakh v norme i osteoartroze. |
| المؤلفون: | Nikolaeva SS; Scientific Research and School-methodical Center for Biomedical Technology, 123056 Moscow, Krasina str. 2., Chkhol KZ, Bykov VA, Roshchina AA, Iakovleva LV, Koroleva OA, Omel'ianenko NP, Rebrov LB |
| المصدر: | Voprosy meditsinskoi khimii [Vopr Med Khim] 2000 Nov-Dec; Vol. 46 (6), pp. 581-90. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Rossiĭskai︠a︡ Akademii︠a︡ Medit︠s︡inskikh Nauk Country of Publication: Russia (Federation) NLM ID: 0416601 Publication Model: Print Cited Medium: Print ISSN: 0042-8809 (Print) Linking ISSN: 00428809 NLM ISO Abbreviation: Vopr Med Khim Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Moskva : Rossiĭskai︠a︡ Akademii︠a︡ Medit︠s︡inskikh Nauk Original Publication: Moskva. |
| مواضيع طبية MeSH: | Cartilage/*metabolism , Hyalin/*metabolism , Osteoarthritis/*metabolism , Water/*metabolism, Adult ; Biological Transport ; Body Water ; Case-Control Studies ; Humans |
| مستخلص: | The content of different forms of tissue water was studied in the normal articular cartilage and osteoarthrosis cartilage and its structural components: collagen, potassium hyaluronate, sodium chondroitinsulphate and its complexes. In the components of cartilage matrix a few of fractions of bound water different in the strength of binding are present. At the maximal humidity, all water in collagen binds with the active groups of biopolymers and in the glycosaminoglycans, in addition to bound water, are present, two crystal forms of freezing water (free water) at least. The quantity of free water in the collagen-chondroitin sulphat membrane, is increased with the increase of chondroitin sulphate. In the collagen-hyaluronate complex, fraction of free water is found only at the low concentration of hyaluronate kalium. It was shown that in the hyalin cartilage, in different from the other connective tissue (skin, achilles tendon), the most part of water is free water and its quantity is increased in the osteoarthrosis. It is supposed that the rearrangement of binding and free-water fractions in the osteoarthrosis is the result of deficiency of hyaluronic acid and therefore this may be regarded in the improvement of methods of treatment. This scientific and methodical approach allow to receive information on the forms and binding energy of water in the biological tissues, which is absorbed from fluids and steam phase and determine characters of the pathological changes. |
| المشرفين على المادة: | 059QF0KO0R (Water) |
| تواريخ الأحداث: | Date Created: 20010310 Date Completed: 20010412 Latest Revision: 20131121 |
| رمز التحديث: | 20221213 |
| PMID: | 11234282 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0042-8809 |
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