دورية أكاديمية

[Leptospirosis after a staff outing].

التفاصيل البيبلوغرافية
العنوان: [Leptospirosis after a staff outing].
عنوان ترانسليتريتد: Leptospirose-Erkrankungen nach einem Betriebsausflug.
المؤلفون: Stephan C; Schwerpunkt Infektiologie, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt am Main. C.Stephan@em.uni-frankfurt.de, Hunfeld KP, Schönberg A, Ott MG, Hetzenecker M, Bitzer R, Just-Nübling G
المصدر: Deutsche medizinische Wochenschrift (1946) [Dtsch Med Wochenschr] 2000 May 19; Vol. 125 (20), pp. 623-7.
نوع المنشور: Case Reports; Journal Article
اللغة: German
بيانات الدورية: Publisher: G. Thieme Country of Publication: Germany NLM ID: 0006723 Publication Model: Print Cited Medium: Print ISSN: 0012-0472 (Print) Linking ISSN: 00120472 NLM ISO Abbreviation: Dtsch Med Wochenschr Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Stuttgart [etc.] : G. Thieme, 1946-
مواضيع طبية MeSH: Leisure Activities* , Leptospira interrogans*/immunology , Water Microbiology*, Leptospirosis/*transmission , Occupational Diseases/*diagnosis, Adult ; Antibodies, Bacterial/blood ; Diagnosis, Differential ; Germany ; Humans ; Leptospirosis/diagnosis ; Leptospirosis/immunology ; Male ; Occupational Diseases/immunology ; Weil Disease/diagnosis ; Weil Disease/immunology
مستخلص: History and Clinical Findings: Three male colleagues aged between 34 and 38 years were admitted at the same time to three different Rhein-Main area Hospitals. They presented with a variety of symptoms, including high fever (39.0 to 40.0 degrees C), chills, headache with meningismus or facial paralysis, mild hepatitis and renal involvement. About 18 days before they had been together on a boat rafting tour when the boat capsized when they had fallen into a river in high flood.
Investigations: Laboratory tests showed elevated inflammatory parameters, signs of a mild hepatitis and renal involvement. All patients had leptospirosis antibodies, detected by immunofluorescence test. In two cases there was evidence of antibodies against Leptospira interrogans serovar bataviae in the microscopic agglutination test (MAT).
Treatment and Course: The history and clinical presentation indicated leptospirosis in all patients, in two cases confirmed by laboratory findings. Following therapy with doxycycline or ceftriaxone, symptoms resolved quickly and permanently.
Conclusion: Leptospires of serogroup Bataviae is a known pathogen of anicteric non-Weil leptospirosis. The symptoms are non-specific and, moreover, in some cases the laboratory tests are negative, so that clinical diagnosis remains crucial. Typically there is a history of contact with contaminated water or urine. In our cases striking neurotropism was observed, which may be characteristic for this serovar.
المشرفين على المادة: 0 (Antibodies, Bacterial)
تواريخ الأحداث: Date Created: 20010321 Date Completed: 20010405 Latest Revision: 20201208
رمز التحديث: 20221213
DOI: 10.1055/s-2007-1024387
PMID: 11256045
قاعدة البيانات: MEDLINE
الوصف
تدمد:0012-0472
DOI:10.1055/s-2007-1024387