دورية أكاديمية
Visual activation in functional magnetic resonance imaging at very high field (4 Tesla).
| العنوان: | Visual activation in functional magnetic resonance imaging at very high field (4 Tesla). |
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| المؤلفون: | Miki A; Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA. amiki@mail.med.upenn.edu, Liu GT, Raz J, Englander SA, Bonhomme GR, Aleman DO, Modestino EJ, Liu CS, Haselgrove JC |
| المصدر: | Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society [J Neuroophthalmol] 2001 Mar; Vol. 21 (1), pp. 8-11. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9431308 Publication Model: Print Cited Medium: Print ISSN: 1070-8022 (Print) Linking ISSN: 10708022 NLM ISO Abbreviation: J Neuroophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <1999->: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: New York, NY : Raven Press, c1994- |
| مواضيع طبية MeSH: | Brain Mapping*, Geniculate Bodies/*physiology , Magnetic Resonance Imaging/*methods , Visual Cortex/*physiology, Adult ; Female ; Humans ; Male ; Photic Stimulation ; Vision, Binocular/physiology |
| مستخلص: | Objectives: Functional magnetic resonance imaging (fMRI) at very high field strengths provides functional brain mapping with the enhanced signal to noise ratio and the larger blood oxygenation level-dependent (BOLD) effect. We report activated areas in the standard space detected by fMRI at 4 Tesla (T) during simple visual stimulation. Materials and Methods: Twelve healthy young subjects were scanned using a 4 T scanner during binocular flashing visual stimulation. Functional images were realigned to the first scan and then spatially normalized. Individual and group data analyses were performed to identify areas of visual activation. Results: Activation of the bilateral primary visual cortex (V1/V2) was observed along the entire calcarine fissure in all subjects. The activated area extended to the extrastriate cortex in all subjects. Activation of the bilateral lateral geniculate nucleus (LGN) was detected in all subjects. The group data showed activation of the bilateral primary visual cortex and the bilateral lateral geniculate nucleus. Conclusions: Robust activation of the vision-related areas was successfully obtained in all subjects using a 4 T magnetic resonance scanner. These results suggest that fMRI at very high field strengths may be effective in showing visual system physiology, and that it can be a promising method to assess visual function of human subjects. |
| تواريخ الأحداث: | Date Created: 20010424 Date Completed: 20010719 Latest Revision: 20191104 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1097/00041327-200103000-00002 |
| PMID: | 11315986 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1070-8022 |
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| DOI: | 10.1097/00041327-200103000-00002 |