دورية أكاديمية

Improving understanding of research consent disclosures among persons with mental illness.

التفاصيل البيبلوغرافية
العنوان: Improving understanding of research consent disclosures among persons with mental illness.
المؤلفون: Stiles PG; Department of Mental Health Law and Policy, Louis de la Parte Florida Mental Health Institute, University of South Florida, Tampa, FL 33612, USA. stiles@fmhi.usf.edu, Poythress NG, Hall A, Falkenbach D, Williams R
المصدر: Psychiatric services (Washington, D.C.) [Psychiatr Serv] 2001 Jun; Vol. 52 (6), pp. 780-5.
نوع المنشور: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.
اللغة: English
بيانات الدورية: Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 9502838 Publication Model: Print Cited Medium: Print ISSN: 1075-2730 (Print) Linking ISSN: 10752730 NLM ISO Abbreviation: Psychiatr Serv Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Washington, DC : American Psychiatric Association, c1995-
مواضيع طبية MeSH: Communication* , Depressive Disorder* , Human Experimentation* , Informed Consent* , Schizophrenia*, Adult ; Female ; Florida ; Humans ; Male ; Mental Competency
مستخلص: Objective: The objective of this study was to evaluate alternative procedures for improving the understanding of research consent disclosures by persons who have mental illness.
Methods: Three groups participated in the study: persons with schizophrenia (N=79), persons with depression (N=82), and a healthy control group (N=80). The participants were guided through an informed consent process in which two factors were manipulated. One was the structure of the disclosure form; either a typical disclosure form involving standard dense text was used, or a graphically enhanced form was used. The other was the interpersonal process: the presence or absence of a third-party facilitator, with iterative feedback given to participants for whom a facilitator was not present. Participants' understanding of the disclosure was assessed with the use of recall tests that involved paraphrasing and recognition tests that involved multiple choice.
Results: The mean understanding scores did not differ significantly between the depression and control groups, and the mean scores of the schizophrenia group were significantly lower than those of the other two groups. Neither the graphically enhanced consent disclosure form nor the presence of a third-party facilitator was associated with improved understanding. The use of iterative feedback was associated with improvement in comprehension scores in all groups.
Conclusions: The use of a feedback procedure in the consent disclosure process during the recruitment of persons who are mentally ill may be a valuable safeguard for ensuring adequate understanding and appropriate participation in research.
معلومات مُعتمدة: R03-MH-56346-01 United States MH NIMH NIH HHS
فهرسة مساهمة: Indexing Agency: KIE Local ID #: 104481.
Keywords: Biomedical and Behavioral Research; Empirical Approach; Mental Health Therapies
Note: 25 refs. Note: KIE Bib: human experimentation/informed consent; human experimentation/special populations
تواريخ الأحداث: Date Created: 20010529 Date Completed: 20010823 Latest Revision: 20071114
رمز التحديث: 20240628
DOI: 10.1176/appi.ps.52.6.780
PMID: 11376225
قاعدة البيانات: MEDLINE
الوصف
تدمد:1075-2730
DOI:10.1176/appi.ps.52.6.780