دورية أكاديمية
[Effect of endogenous nitric oxide on the nerve-muscle synapse function].
| العنوان: | [Effect of endogenous nitric oxide on the nerve-muscle synapse function]. |
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| عنوان ترانسليتريتد: | Vliianie éndogennogo oksida azota na funktsiiu nervno-myshechnogo sinapsa. |
| المؤلفون: | Zefirov AL; Kazan State Medical University, Kazan, Butlerov St., 49, 420012., Khaliullina RR, Anuchin AA, Iakovlev AV |
| المصدر: | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2001 Apr; Vol. 87 (4), pp. 499-506. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Nauka Country of Publication: Russia (Federation) NLM ID: 9715665 Publication Model: Print Cited Medium: Print ISSN: 0869-8139 (Print) Linking ISSN: 08698139 NLM ISO Abbreviation: Ross Fiziol Zh Im I M Sechenova Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: S.-Peterburg : Nauka Original Publication: Sankt-Peterburg : "Nauka", c1997- |
| مواضيع طبية MeSH: | Neuromuscular Junction/*physiology , Nitric Oxide/*biosynthesis, Animals ; Arginine/pharmacology ; Electric Stimulation ; Enzyme Inhibitors/pharmacology ; In Vitro Techniques ; Neuromuscular Junction/drug effects ; Neuromuscular Junction/metabolism ; Nitric Oxide Synthase/antagonists & inhibitors ; Nitroarginine/pharmacology ; Rana ridibunda |
| مستخلص: | The nitric oxide (NO) precursor L-arginine was found to decrease the amplitude and the quantum content of the EPPs and to increase the amplitude of the AP third deflection in the frog neuromuscular junction of the m. cutaneous pectoris preparation. Inhibitor of the NO synthase NG-nitro-L-arginine methylester exerted opposite effects. The data obtained suggest that endogenous NO is produced in the neuromuscular synapse area and can modify the work of potassium ion channels. |
| المشرفين على المادة: | 0 (Enzyme Inhibitors) 2149-70-4 (Nitroarginine) 31C4KY9ESH (Nitric Oxide) 94ZLA3W45F (Arginine) EC 1.14.13.39 (Nitric Oxide Synthase) |
| تواريخ الأحداث: | Date Created: 20010714 Date Completed: 20010802 Latest Revision: 20161020 |
| رمز التحديث: | 20231215 |
| PMID: | 11449977 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0869-8139 |
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