دورية أكاديمية
[Experiences with niflumic acid in inflammatory glomerulopathies].
| العنوان: | [Experiences with niflumic acid in inflammatory glomerulopathies]. |
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| عنوان ترانسليتريتد: | Erfahrungen mit Nifluminsäure bei entzündlichen glomerulären Erkrankungen |
| المؤلفون: | Boeckle H, Oechslen D, Lüttgen F, Lindenmaier K |
| المصدر: | Arzneimittel-Forschung [Arzneimittelforschung] 1975 Jan; Vol. 25 (1), pp. 120-2. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | German |
| بيانات الدورية: | Publisher: Editio Cantor Country of Publication: Germany NLM ID: 0372660 Publication Model: Print Cited Medium: Print ISSN: 0004-4172 (Print) Linking ISSN: 00044172 NLM ISO Abbreviation: Arzneimittelforschung Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Aulendorf, Editio Cantor |
| مواضيع طبية MeSH: | Glomerulonephritis/*drug therapy , Nicotinic Acids/*therapeutic use , Niflumic Acid/*therapeutic use , Proteinuria/*drug therapy, Depression, Chemical ; Female ; Fibrinogen/metabolism ; Humans ; Male ; Nephrotic Syndrome/drug therapy |
| مستخلص: | Thirty patients with histologically ascertained blomerulonephritis and proteinuria were treated over an average period of 4 months with 750 mg/die 2-m-trigluoromethylanilino-nicotinic acid (niflumic acid, Actol). The following was shown: 1. In 73% of the cases the proteinuria diminished. 2. Kidney function remained unchanged, that is, it worsened only in such cases in which there was already limited functioning. 3. In case of initially increased values the secretion of fibrinogen degradation products diminished in 70% of the cases. 4. When the medication was stopped, its effects vanished. Niflumic acid shows to be an effective drug in the treatment of the nephrotic syndrome and the number of complications is smaller due to the improved condition of protein metabolism. Therefore, this form of treatment, in certain ways, influences the prognosis of the disease. |
| المشرفين على المادة: | 0 (Nicotinic Acids) 4U5MP5IUD8 (Niflumic Acid) 9001-32-5 (Fibrinogen) |
| تواريخ الأحداث: | Date Created: 19750101 Date Completed: 19750929 Latest Revision: 20131121 |
| رمز التحديث: | 20231215 |
| PMID: | 1173764 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0004-4172 |
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