دورية أكاديمية
Soil-transmitted nematode infections and mebendazole treatment in Mafia Island schoolchildren.
| العنوان: | Soil-transmitted nematode infections and mebendazole treatment in Mafia Island schoolchildren. |
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| المؤلفون: | Albonico M; Ivo de Carneri Foundation, Via IV Marzo 14, 10122, Torino, Italy., Ramsan M, Wright V, Jape K, Haji HJ, Taylor M, Savioli L, Bickle Q |
| المصدر: | Annals of tropical medicine and parasitology [Ann Trop Med Parasitol] 2002 Oct; Vol. 96 (7), pp. 717-26. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 2985178R Publication Model: Print Cited Medium: Print ISSN: 0003-4983 (Print) Linking ISSN: 00034983 NLM ISO Abbreviation: Ann Trop Med Parasitol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Abingdon : Taylor & Francis Original Publication: London : Academic Press |
| مواضيع طبية MeSH: | Ascaris lumbricoides* , Trichuris*, Antinematodal Agents/*therapeutic use , Hookworm Infections/*drug therapy , Mebendazole/*therapeutic use , Nematode Infections/*drug therapy , Soil/*parasitology, Adolescent ; Anemia/parasitology ; Animals ; Child ; Cross-Sectional Studies ; Demography ; Drug Resistance ; Female ; Hookworm Infections/complications ; Hookworm Infections/epidemiology ; Humans ; Male ; Nematode Infections/complications ; Nematode Infections/epidemiology ; Parasite Egg Count ; Prevalence ; Tanzania/epidemiology |
| مستخلص: | In August 2000, a cross-sectional study was performed to assess the prevalence and intensity of soil-transmitted nematode infections in schoolchildren on Mafia Island. Hookworm infection was widespread (72.5% prevalence) whereas Trichuris trichiura was less prevalent (39.7%) and Ascaris lumbricoides was present at a low prevalence (4.2%), mainly in urban areas. In a subsample of the study population, both Necator americanus and Ancylostoma duodenale were found, although N. americanus was more prevalent. This survey was followed by a parasitological evaluation of mebendazole treatment using a single, 500-mg dose. The data on outcome were used for comparison with those from recent studies of similar treatment regimens in the neighbouring island of Pemba, Zanzibar, where periodic chemotherapy with mebendazole to schoolchildren has been implemented as part of a helminth-control programme since 1994. A higher efficacy of mebendazole against hookworm infection was found in Mafia Island (where a cure 'rate' of 31.3% and an egg-reduction 'rate' of 78.1% were recorded) when compared with that observed in Pemba Island, possibly indicating that hookworms may be developing mebendazole resistance on Pemba Island as a result of intense exposure to the drug there. |
| المشرفين على المادة: | 0 (Antinematodal Agents) 0 (Soil) 81G6I5V05I (Mebendazole) |
| تواريخ الأحداث: | Date Created: 20030123 Date Completed: 20030328 Latest Revision: 20171116 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1179/000349802125001942 |
| PMID: | 12537633 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 0003-4983 |
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| DOI: | 10.1179/000349802125001942 |