دورية أكاديمية
[Prognostic value of troponin T in hospitalized patients with angina or non-ST-segment elevation myocardial infarction].
| العنوان: | [Prognostic value of troponin T in hospitalized patients with angina or non-ST-segment elevation myocardial infarction]. |
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| عنوان ترانسليتريتد: | Valor pronóstico de la tropinina T en pacientes hospitalizados con angina o infarto sin elevación del segmento ST. |
| المؤلفون: | Roldán Torres I; Servicio de Cardiología, Hospital Universitario Dr. Peset, Valencia, Spain. il.roldant@comv.es, Baello Monge P, Sevilla Toral B, Salvador Sanz A, Salim Martínez M, Peláez González A, Mora Llabata V, Martínez Diago V, Morales Suárez-Varela M, Martínez-Triguero ML, Molina Andreu E |
| المصدر: | Revista espanola de cardiologia [Rev Esp Cardiol] 2003 Jan; Vol. 56 (1), pp. 35-42. |
| نوع المنشور: | Comparative Study; English Abstract; Journal Article |
| اللغة: | Spanish; Castilian |
| بيانات الدورية: | Publisher: Elsevier España Country of Publication: Spain NLM ID: 0404277 Publication Model: Print Cited Medium: Print ISSN: 0300-8932 (Print) Linking ISSN: 03008932 NLM ISO Abbreviation: Rev Esp Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2009-> : Madrid : Elsevier España Original Publication: Madrid : Sociedad Española de Cardiología |
| مواضيع طبية MeSH: | Troponin T*/blood, Angina, Unstable/*diagnosis , Myocardial Infarction/*diagnosis, Adult ; Aged ; Aged, 80 and over ; Angina, Unstable/blood ; Biomarkers/blood ; Electrocardiography ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Myocardial Infarction/blood ; Prognosis ; Retrospective Studies |
| مستخلص: | Introduction and Objectives: Cardiac troponins are highly specific and sensitive for detecting minimal myocardial damage. The aim of our study was to determine the prognostic value of troponin T levels in patients hospitalized for suspected angina or myocardial infarction without ST-segment elevation. Patients and Method: We recorded the frequency of death, acute myocardial infarction, heart failure, or need for coronary revascularization in the three months after the onset of symptoms in 346 consecutive patients admitted for suspected acute coronary syndrome, excluding those who developed myocardial infarction with persistent ST-segment elevation. Result: . Serum troponin T levels were > or = 0.1 ng/ml in 133 patients (troponin T positive group) and lower in 213 patients (troponin T negative group). The relative risk (RR) and 95 percent confidence intervals (95% CI) of individual and grouped events for the troponin T positive group were 3.2 (95% CI, 1.4-7.3; p = 0.006) for death; 2.8 (95% CI, 1.43-5.51; p = 0.003) for death or myocardial infarction; and 2.8 (95% CI, 1.6-5.0; p < 0.001) for death, myocardial infarction or heart failure. Diabetes mellitus and troponin T levels > or = 0.1 ng/ml had independent prognostic value after adjusting for age, sex, and electrocardiographic changes; with RR 2.5 (95% CI, 1.01-5.9) for death, myocardial infarction or heart failure. Conclusions: The prognosis of patients hospitalized for chest pain who do not immediately develop transmural necrosis depends on serum troponin T levels at hospital admission. Troponin T levels > or = 0.1 ng/ml almost triple the risk of major events in the three months after the acute episode. The prognostic value of troponin T is independent of age, sex, presence of diabetes mellitus, and electrocardiographic changes. |
| التعليقات: | Comment in: Rev Esp Cardiol. 2003 Jan;56(1):16-9. (PMID: 12549994) |
| المشرفين على المادة: | 0 (Biomarkers) 0 (Troponin T) |
| تواريخ الأحداث: | Date Created: 20030129 Date Completed: 20030523 Latest Revision: 20190916 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1016/s0300-8932(03)76819-5 |
| PMID: | 12549998 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0300-8932 |
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| DOI: | 10.1016/s0300-8932(03)76819-5 |