دورية أكاديمية
أعرض في EDS

Plasma homocysteine, angiographically proven coronary artery disease, and wine consumption.

التفاصيل البيبلوغرافية
العنوان: Plasma homocysteine, angiographically proven coronary artery disease, and wine consumption.
المؤلفون: Toft E; Department of Cardiology, Aalborg Hospital, Arhus University Hospital, Aalborg, Denmark, Ellegaard Hansen V, Hagstrup Christensen J, Berg Schmidt E, Aarup Skou H, Fog L, Ekelund S, Dyerberg J
المصدر: European journal of internal medicine [Eur J Intern Med] 2003 Jul; Vol. 14 (4), pp. 244-248.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9003220 Publication Model: Print Cited Medium: Internet ISSN: 1879-0828 (Electronic) Linking ISSN: 09536205 NLM ISO Abbreviation: Eur J Intern Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 1999- : Amsterdam, The Netherlands : Elsevier Science
Original Publication: Basingstoke, Hampshire, UK : Published by the Macmillan Press on behalf of the European Association of Internal Medicine, c1989-
مستخلص: BACKGROUND: Plasma total homocysteine (p-tHcy) is considered to be an independent risk factor for atherosclerotic vascular disease. This cross-sectional study was undertaken to examine p-tHcy levels and their relationship to coronary artery disease (CAD) and alcohol intake. METHODS: We consecutively studied 291 patients referred for elective coronary angiography due to suspected CAD. The patients completed an alcohol questionnaire, and blood samples were drawn after an overnight fast for measurement of p-tHcy. RESULTS: Patients without CAD (n=85) had significantly lower p-tHcy (10.1+/-4.7 μmol/l) than patients with at least one significant coronary artery stenosis (n=206, p-tHcy: 11.9+/-6.4 μmol/l). Patients with a previous myocardial infarction (MI; n=74) also had a higher p-tHcy (12.3+/-4.0 μmol/l) than patients without MI (n=217; p-tHcy: 10.7+/-6.2 μmol/l). Patients with a daily intake of wine (n=30) had lower p-tHcy (9.4+/-2.8 μmol/l) than patients who did not drink wine (n=47; p-tHcy: 12.1+/-6.0 μmol/l; P<0.05), independent of age, prior MI, and degree of CAD. CONCLUSIONS: p-tHcy correlated positively with CAD. There was an inverse correlation between p-tHcy and wine consumption, suggesting a new potential mechanism by which wine consumption may lower the risk of CAD.
تواريخ الأحداث: Date Created: 20030816 Latest Revision: 20191120
رمز التحديث: 20231215
DOI: 10.1016/s0953-6205(03)00069-4
PMID: 12919840
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-0828
DOI:10.1016/s0953-6205(03)00069-4