دورية أكاديمية
Diagnostic accuracy of mammography and scintimammography in detection of primary breast cancer related size of the tumour.
| العنوان: | Diagnostic accuracy of mammography and scintimammography in detection of primary breast cancer related size of the tumour. |
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| المؤلفون: | Cwikła JB; Department of Radiology; SPSK Otwock, Poland., Buscombe JR, Chaberek S, Holloway B, Parbhoo S, Hilson AJ |
| المصدر: | Nuclear medicine review. Central & Eastern Europe [Nucl Med Rev Cent East Eur] 2000; Vol. 3 (2), pp. 127-32. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Via Medica Country of Publication: Poland NLM ID: 100886103 Publication Model: Print Cited Medium: Print ISSN: 1506-9680 (Print) Linking ISSN: 15069680 NLM ISO Abbreviation: Nucl Med Rev Cent East Eur Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Gdańsk, Poland : Via Medica , 1998- |
| مستخلص: | Background: The detection of breast cancer relies on physical examination and mammography (XMM). The sensitivity of conventional imaging is lesions-size dependent. However, mammography has good sensitivity in small tumours when microcalcification is present, but the sensitivity is relatively low in other small tumours. The use of scintimammography with Tc-99m sestaMIBI (SMM) may be helpful in this situation. The aim of this study is to compare the diagnostic accuracy of mammography and scintimammography across all groups with different sizes of lesions. Methods: Data for 273 patients aged 26 to 84 years (mean 52; SD 12) with 298 lesions were analysed. All lesions were removed and final histology and pathological size of the tumours were retrospectively reviewed (mean size 2.9 cm, SD 2.4 cm). All patients had XMM and SMM. Each imaging study was graded using five grades of certainty. SMM images were reviewed by an independent specialist blinded to clinical presentation and XMM results. The diagnostic accuracy of each test, overall and by each lesions size subgroup, was compared using receiver operating characteristic curve (ROC) analysis. Results: The sensitivity of scintimammography was consistently high across all size groups; overall 89% (82?100%) compared with 68% (51?88%) for mammography. In those tumours below 2 cm, the area under the ROC was significantly larger with SMM than XMM (p < 0.05), with 80% certainty indicative of greater diagnostic accuracy. Also in all patients the area under the ROC was significantly larger with SMM than XMM (p < 0.05), with 90% certainty indicative of greater diagnostic accuracy. In other groups of lesions size the area under ROC for SMM was larger in lesions size between 2 and 4 cm and slightly smaller in lesions over 4 cm, but it was not significant. Conclusion: Scintimammography using Tc-99m sestaMIBI seems to be a sensitive and consistently reliable diagnostic test for breast cancer independent of the size of the tumour. |
| تواريخ الأحداث: | Date Created: 20031106 Date Completed: 20040115 Latest Revision: 20111013 |
| رمز التحديث: | 20221213 |
| PMID: | 14600905 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1506-9680 |
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