دورية أكاديمية
Instrumentation for multi-modal spectroscopic diagnosis of epithelial dysplasia.
العنوان: | Instrumentation for multi-modal spectroscopic diagnosis of epithelial dysplasia. |
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المؤلفون: | Tunnell JW; G.R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Ave., Bldg 6-014, Cambridge, MA 02139, USA., Desjardins AE, Galindo L, Georgakoudi I, McGee SA, Mirkovic J, Mueller MG, Nazemi J, Nguyen FT, Wax A, Zhang Q, Dasari RR, Feld MS |
المصدر: | Technology in cancer research & treatment [Technol Cancer Res Treat] 2003 Dec; Vol. 2 (6), pp. 505-14. |
نوع المنشور: | Journal Article; Research Support, U.S. Gov't, P.H.S. |
اللغة: | English |
بيانات الدورية: | Publisher: SAGE Country of Publication: United States NLM ID: 101140941 Publication Model: Print Cited Medium: Print ISSN: 1533-0346 (Print) Linking ISSN: 15330338 NLM ISO Abbreviation: Technol Cancer Res Treat Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2015-: Thousand Oaks, CA : SAGE Original Publication: Schenectady, NY : Adenine Press, c2002- |
مواضيع طبية MeSH: | Carcinoma/*diagnosis , Epithelium/*pathology , Spectrum Analysis/*instrumentation, Fiber Optic Technology ; Humans ; Optics and Photonics ; Phantoms, Imaging ; Software ; Spectrometry, Fluorescence/instrumentation |
مستخلص: | Reflectance and fluorescence spectroscopies have shown great promise for early detection of epithelial dysplasia. We have developed a clinical reflectance spectrofluorimeter for multimodal spectroscopic diagnosis of epithelial dysplasia. This clinical instrument, the FastEEM, collects white light reflectance and fluorescence excitation-emission matrices (EEM's) within a fraction of a second. In this paper we describe the FastEEM instrumentation, designed for collection of multi-modal spectroscopic data. We illustrate its performance using tissue phantoms with well defined optical properties and biochemicals of known fluorescence properties. In addition, we discuss our plans to develop a system that combines a multi-spectral imaging device for wide area surveillance with this contact probe device. |
معلومات مُعتمدة: | P41-RR02594 United States RR NCRR NIH HHS; R01-CA97966 United States CA NCI NIH HHS |
تواريخ الأحداث: | Date Created: 20031204 Date Completed: 20040714 Latest Revision: 20170214 |
رمز التحديث: | 20221213 |
DOI: | 10.1177/153303460300200603 |
PMID: | 14640762 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1533-0346 |
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DOI: | 10.1177/153303460300200603 |