دورية أكاديمية
Fibrin sealant reduces perioperative blood loss in total hip replacement.
| العنوان: | Fibrin sealant reduces perioperative blood loss in total hip replacement. |
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| المؤلفون: | Wang GJ; Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, USA., Goldthwaite CA Jr, Burks S, Crawford R, Spotnitz WD |
| مؤلفون مشاركون: | Orthopaedic Investigators Group |
| المصدر: | Journal of long-term effects of medical implants [J Long Term Eff Med Implants] 2003; Vol. 13 (5), pp. 399-411. |
| نوع المنشور: | Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Begell House Country of Publication: United States NLM ID: 9110830 Publication Model: Print Cited Medium: Print ISSN: 1050-6934 (Print) Linking ISSN: 10506934 NLM ISO Abbreviation: J Long Term Eff Med Implants |
| أسماء مطبوعة: | Publication: <2003-> : New York, NY : Begell House Original Publication: Boca Raton : CRC Press, c1991- |
| مواضيع طبية MeSH: | Arthroplasty, Replacement, Hip/*methods , Fibrin Tissue Adhesive/*therapeutic use , Intraoperative Complications/*prevention & control , Postoperative Hemorrhage/*prevention & control, Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Single-Blind Method |
| مستخلص: | Patients (n = 81) undergoing total hip replacement (THR) were randomized to receive either standard of care plus fibrin sealant (FS) (10 mL total) or standard of care alone to evaluate the efficacy of FS for reducing blood loss in THR. Considering the 81 intent-to-treat patients, adjusted perioperative blood loss was reduced significantly in the FS group, by 197 mL [95% CI: 45 mL, 319 mL] or 23.5% [95% CI: 5.4%, 38.1%] (p = 0.014). When protocol violators were eliminated, leaving 73 patients, the adjusted FS group perioperative bleeding was reduced by 221 mL [95% CI: 63 mL, 351 mL] or 27.1% [95% CI: 7.6%, 42.5%] (p = 0.0098). |
| التعليقات: | Comment in: J Long Term Eff Med Implants. 2003;13(5):385-7. (PMID: 14649576) |
| المشرفين على المادة: | 0 (Fibrin Tissue Adhesive) |
| تواريخ الأحداث: | Date Created: 20031203 Date Completed: 20040129 Latest Revision: 20191108 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1615/jlongtermeffmedimplants.v13.i5.50 |
| PMID: | 14649578 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1050-6934 |
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| DOI: | 10.1615/jlongtermeffmedimplants.v13.i5.50 |