دورية أكاديمية
[Effects of Semen Sojae Preparatum on lipid metabolism in ovariectomized rat].
| العنوان: | [Effects of Semen Sojae Preparatum on lipid metabolism in ovariectomized rat]. |
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| المؤلفون: | Wang X; Traditional Chinese Medicine College, Hebei Medical University, Shijiazhuang 050091., Ge X, Bai X, Song C, Niu L, Xu H |
| المصدر: | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials [Zhong Yao Cai] 2003 Sep; Vol. 26 (9), pp. 652-4. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Guo jia yi yao guan li ju Zhong yao cai qing bao zhong xin zhan Country of Publication: China NLM ID: 9426370 Publication Model: Print Cited Medium: Print ISSN: 1001-4454 (Print) Linking ISSN: 10014454 NLM ISO Abbreviation: Zhong Yao Cai Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Guangzhou Shi : Guo jia yi yao guan li ju Zhong yao cai qing bao zhong xin zhan Original Publication: Guangzhou Shi : Guo jia yi yao guan li ju Zhong yao cai qing bao zhong xin zhan, |
| مواضيع طبية MeSH: | Lipid Metabolism*, Arteriosclerosis/*prevention & control , Drugs, Chinese Herbal/*pharmacology , Glycine max/*chemistry, Animals ; Female ; Lipid Peroxidation ; Ovariectomy ; Plants, Medicinal/chemistry ; Random Allocation ; Rats ; Rats, Sprague-Dawley |
| مستخلص: | Objective: To investigate the antiatherosclerotic effect of Semen Sojae Preparatum (SSP) and its mechanism. Methods: 48 rats were randomly divided into sham operation group (sham), ovariectomized group (OVX) and three doses of OVX + SSP groups. SSP was given to OVX + SSP groups 2 weeks after ovariectomy. The levels of serum lipids and lipid peroxidation were detected after 12 weeks treatment. Results: SSP lowered serum oxidized-low density lipoprotein cholesterol (OX-LDL, P < 0.01), triglyceride (TG, P < 0.01) and malondialdehyde (MDA, P < 0.05 or P < 0.01), and enhanced serum high density lipoprotein cholesterol (HDL-c, P < 0.05 or P < 0.01), polipoprotein A I (apo-AI, P < 0.01) and superoxide dismutase (SOD, P < 0.01) activity. Conclusion: SSP had effects on regulating lipid and antioxidation. Therefore, it might inhibit atherosclerosis in ovariectomy rats. |
| المشرفين على المادة: | 0 (Drugs, Chinese Herbal) |
| تواريخ الأحداث: | Date Created: 20031225 Date Completed: 20040309 Latest Revision: 20231213 |
| رمز التحديث: | 20231215 |
| PMID: | 14692323 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1001-4454 |
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