دورية أكاديمية
Cardiac parasympathetic dysfunction related to depression in older adults with acute coronary syndromes.
| العنوان: | Cardiac parasympathetic dysfunction related to depression in older adults with acute coronary syndromes. |
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| المؤلفون: | Guinjoan SM; Department of Mental Health and Coronary Care Unit, Hospital de Clínicas 'José de San Martín', University of Buenos Aires School of Medicine, Buenos Aires, Argentina. guinjoan@fmed.uba.ar, de Guevara MS, Correa C, Schauffele SI, Nicola-Siri L, Fahrer RD, Ortiz-Frágola E, Martínez-Martínez JA, Cardinali DP |
| المصدر: | Journal of psychosomatic research [J Psychosom Res] 2004 Jan; Vol. 56 (1), pp. 83-8. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 0376333 Publication Model: Print Cited Medium: Print ISSN: 0022-3999 (Print) Linking ISSN: 00223999 NLM ISO Abbreviation: J Psychosom Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Pergamon Press Original Publication: London. |
| مواضيع طبية MeSH: | Coronary Disease/*psychology , Depressive Disorder, Major/*epidemiology , Depressive Disorder, Major/*physiopathology , Heart Rate/*physiology , Parasympathetic Nervous System/*physiopathology, Acute Disease ; Adult ; Aged ; Coronary Disease/epidemiology ; Cross-Sectional Studies ; Depressive Disorder, Major/diagnosis ; Female ; Humans ; Middle Aged |
| مستخلص: | Objective: To determine whether depression is associated with cardiac autonomic alterations in elderly patients with recent acute coronary syndromes (ACSs). Methods: Cross-sectional study on the association between a major depressive episode or isolated depressive symptoms (21-item Hamilton depression score) and heart rate variability abnormalities in 56 adults (31 women, 55%) 60 years of age and older with a recent (24-72 h) myocardial infarction (MI) or unstable angina (UA). Results: Spectral and nonspectral parameters of respiratory sinus arrhythmia, indicative of parasympathetic activity on the heart, were decreased in patients with depression (high-frequency heart rate variability [log ms(2)] 2.12+/-0.4 vs. 2.52+/-0.5, P=.024; pNN50 [%] 1+/-2 vs. 9+/-15, P=.006; and rMSNN [ms] 16+/-6 vs. 28+/-22, P=.009). Also, high-frequency heart rate variability decreased with increasing depressive symptom severity. Conclusion: In a sample of older adults suffering from ACSs, depression was associated with impaired parasympathetic control of the heart. |
| تواريخ الأحداث: | Date Created: 20040228 Date Completed: 20040701 Latest Revision: 20220409 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/S0022-3999(03)00043-6 |
| PMID: | 14987968 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0022-3999 |
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| DOI: | 10.1016/S0022-3999(03)00043-6 |