التفاصيل البيبلوغرافية
العنوان: |
Direct comparison between Czerny-Lembert and circular-stapled anastomotic techniques in colorectal anastomosis: a similar pattern of healing for both. |
المؤلفون: |
Senagore A; Department of Surgical Research, Ferguson Clinic, Grand Rapids, Michigan., Milsom JW, Walshaw RK, Dunston R, Chaudry IH |
المصدر: |
Diseases of the colon and rectum [Dis Colon Rectum] 1992 Sep; Vol. 35 (9), pp. 862-9. |
نوع المنشور: |
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: |
English |
بيانات الدورية: |
Publisher: Lippincott Country of Publication: United States NLM ID: 0372764 Publication Model: Print Cited Medium: Print ISSN: 0012-3706 (Print) Linking ISSN: 00123706 NLM ISO Abbreviation: Dis Colon Rectum Subsets: MEDLINE |
أسماء مطبوعة: |
Original Publication: Philadelphia. Lippincott |
مواضيع طبية MeSH: |
Surgical Staplers* , Suture Techniques* , Wound Healing*, Colon/*surgery , Rectum/*surgery, Anastomosis, Surgical/methods ; Animals ; Collagen/biosynthesis ; Colon/blood supply ; Colon/pathology ; Colon/physiology ; Female ; Inflammation/pathology ; Random Allocation ; Rectum/blood supply ; Rectum/pathology ; Rectum/physiology ; Swine ; Tensile Strength |
مستخلص: |
There are scant experimental data directly comparing the healing of the circular-stapled (CS) anastomotic technique with the standard Czerny-Lembert two-layer hand-sewn (HS) anastomotic technique during the acute and chronic phases of healing. The purpose of this study, therefore, was to serially evaluate wound healing in CS and HS anastomoses in the normal porcine colorectum. Forty-two adult female mixed-breed pigs randomly underwent either HS or CS anastomosis at the sacral promontory. Laser Doppler velocimetry (LDV), was used to measure perianastomotic blood flow. Groups of animals underwent a second surgery at 3, 5, 11, 60, or 120 days postoperatively, and anastomoses were restudied using LDV, gross and microscopic grading of inflammation, bursting pressures, and hydroxyproline content. Additionally, the 60-day and 120-day groups of animals underwent preoperative biplanar barium enemas to identify leaks or stenoses. No significant differences in perianastomotic blood flow between the HS and CS techniques were obtained over the entire 120-day study period. Serial evaluation of wound healing revealed no significant differences between the two anastomotic techniques with respect to bursting pressures, gross or microscopic inflammatory scores, or hydroxyproline content. There were no leaks or stenoses with either technique. Despite earlier reports to the contrary, there appears to be no fundamental difference in the mode of healing in the porcine colorectum comparing the HS technique with the CS technique. |
المشرفين على المادة: |
9007-34-5 (Collagen) |
تواريخ الأحداث: |
Date Created: 19920901 Date Completed: 19920929 Latest Revision: 20190721 |
رمز التحديث: |
20231215 |
DOI: |
10.1007/BF02047874 |
PMID: |
1511647 |
قاعدة البيانات: |
MEDLINE |