دورية أكاديمية
Report of unusual clinical appearance in bacteraemia with nonhaemolytic M-type 58 Streptococcus pyogenes.
| العنوان: | Report of unusual clinical appearance in bacteraemia with nonhaemolytic M-type 58 Streptococcus pyogenes. |
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| المؤلفون: | Weightman NC; Department of Microbiology, Friarage Hospital, Northallerton, UK. nigel.weightman@stees.nhs.uk, Barnham MR |
| المصدر: | The Indian journal of medical research [Indian J Med Res] 2004 May; Vol. 119 Suppl, pp. 17-21. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Country of Publication: India NLM ID: 0374701 Publication Model: Print Cited Medium: Print ISSN: 0971-5916 (Print) Linking ISSN: 09715916 NLM ISO Abbreviation: Indian J Med Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2011- > : Mumbai : Medknow Original Publication: New Delhi : Council Of Medical Research |
| مواضيع طبية MeSH: | Bacteremia/*physiopathology , Streptococcus pyogenes/*isolation & purification, Aged ; Bacteremia/microbiology ; Humans ; Male |
| مستخلص: | Background & Objectives: The occurrence of haemolytic colonies on blood agar often provides the starting point for the laboratory diagnosis of pyogenic streptococci, while non-haemolytic variants could pass unrecognised, leading to a failure of diagnosis. We report the details of two epidemiologically unrelated patients with bacteraemia featuring M-type 58 Streptococcus pyogenes, a seemingly rare cause of human infection in the UK, and briefly review previous reports of infection with non-haemolytic strains of this species. Methods: Case notes of the two patients were reviewed. Isolates obtained from clinical specimens were recovered and identified and cultured on horse blood agar to observe pattern of haemolysis. Results: In the first case, of a 75 year-old man with leukaemia and a retropharyngeal abscess, the isolate was consistently non-haemolytic, probably due to a failure to produce streptolysin S as has been described before in a small number of reports involving various M-types. In the second case, of an 84 year-old woman with dermatitis and septicaemia, the organism was principally beta-haemolytic but with no haemolysis on aerobic culture where the colonies were well spaced, a phenomenon thought to be associated with abundant production of serum opacity factor (OF). Interpretation & Conclusion: These cases are a reminder that misleading cultural appearances can occur with S. pyogenes and that OF positive strains can produce poor haemolysis on aerobic culture, or fail even to do so at all. |
| تواريخ الأحداث: | Date Created: 20040703 Date Completed: 20041013 Latest Revision: 20130418 |
| رمز التحديث: | 20221213 |
| PMID: | 15232155 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0971-5916 |
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