دورية أكاديمية

[A new applicator with regulatable air bag designed for intracavitary brachytherapy of nasopharyngeal carcinoma].

التفاصيل البيبلوغرافية
العنوان: [A new applicator with regulatable air bag designed for intracavitary brachytherapy of nasopharyngeal carcinoma].
المؤلفون: Zhang N; Department of Radiation Oncology, The First People's Hospital of Foshan City, Foshan, Guangdong, 528041, P.R.China. z7751@21cn.com, Wei GY, Tan YC, Huang ZL, Li SE, Lu ZQ
المصدر: Ai zheng = Aizheng = Chinese journal of cancer [Ai Zheng] 2004 Oct; Vol. 23 (10), pp. 1222-4.
نوع المنشور: English Abstract; Journal Article
اللغة: Chinese
بيانات الدورية: Publisher: Zhongshan da xue zhong liu fang zhi zhong xin Country of Publication: China NLM ID: 9424852 Publication Model: Print Cited Medium: Print NLM ISO Abbreviation: Ai Zheng Subsets: MEDLINE
أسماء مطبوعة: Manufacture: <2009- > : Guangzhou : Zhongshan da xue zhong liu fang zhi zhong xin
Original Publication: Guangzhou : Zhongshan yi ke da xue Fu shu zhong liu yi yuan
مواضيع طبية MeSH: Brachytherapy/*instrumentation , Carcinoma, Squamous Cell/*radiotherapy , Nasopharyngeal Neoplasms/*radiotherapy, Adolescent ; Adult ; Aged ; Brachytherapy/methods ; Cobalt Radioisotopes/therapeutic use ; Equipment Design ; Equipment Safety ; Female ; Humans ; Male ; Middle Aged ; Treatment Outcome
مستخلص: Background & Objective: Nasopharynx applicator used in intracavitary brachytherapy plays an important role in the radiotherapy of nasopharyngeal carcinoma (NPC), its quality affects the efficiency of treatment. This study was to design a new applicator for clinical use.
Methods: An inexpensive, reusable, and flexible latex nasopharynx applicator was designed. An air bag was placed at 15 mm from the foreside of the applicator, clung to the tube. The edge of air bag is tangent to the axis of tube. When the bag was full of air, the tube would hunch reversely,close to nasopharyngeal vault. After introduced into nasopharynx through middle nasal meatus, the applicator could be fixed in suitable position by its rotation, and air bag regulation, and confirmed its position by simulation.
Results: A total of 221 patients with NPC were treated with external beam radiation therapy in our hospital, and boosted HDR brachytherapy using this new applicator. The response rate was 92.6% in the primary tumor group (200/216), and 100% in the recurrent tumor group (5/5). Mucosal necrosis in the posterior or anterior wall of nasopharynx occurred in 5 patients, 8 patients experienced nasal congestion and nasal synechia.
Conclusions: This new nasopharynx applicator is easy to operate, painless, and well dosage-distributed. Mucosal necrosis is likely due to higher fractional dose.
المشرفين على المادة: 0 (Cobalt Radioisotopes)
تواريخ الأحداث: Date Created: 20041012 Date Completed: 20050815 Latest Revision: 20150313
رمز التحديث: 20240628
PMID: 15473941
قاعدة البيانات: MEDLINE