دورية أكاديمية
DNA-modified carbon paste electrode applied to the study of interaction between rifampicin (RIF) and DNA in solution and at the electrode surface.
| العنوان: | DNA-modified carbon paste electrode applied to the study of interaction between rifampicin (RIF) and DNA in solution and at the electrode surface. |
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| المؤلفون: | Girousi ST; Analytical Chemistry Laboratory, Department of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. girousi@chem.auth.gr, Gherghi ICh, Karava MK |
| المصدر: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2004 Nov 19; Vol. 36 (4), pp. 851-8. |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print Cited Medium: Print ISSN: 0731-7085 (Print) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2006->: London : Elsevier Science Original Publication: Oxford ; New York : Pergamon Press, c1983- |
| مواضيع طبية MeSH: | Carbon/*analysis , DNA/*analysis , Rifampin/*analysis, Animals ; Cattle ; DNA/metabolism ; Electrochemistry ; Electrodes/standards ; Rifampin/chemistry ; Rifampin/metabolism ; Solutions |
| مستخلص: | Rifampicin (RIF) is an antibiotic widely used against tuberculosis and a DNA intercalator. The interaction of RIF with double-stranded (ds) and single-stranded (ss) calf thymus DNA was studied in solution as well as at the electrode surface by means of transfer voltammetry using differential pulse as stripping mode with carbon paste electrode (CPE) at 0.2M acetate buffer at pH 5.0 and at 0.2M phosphate buffer pH 7.4. Differentiations in the above-mentioned interaction at different pH values are presented and compared in order to optimize the detection of Rifampicin (RIF). |
| المشرفين على المادة: | 0 (Solutions) 7440-44-0 (Carbon) 9007-49-2 (DNA) 91080-16-9 (calf thymus DNA) VJT6J7R4TR (Rifampin) |
| تواريخ الأحداث: | Date Created: 20041110 Date Completed: 20050412 Latest Revision: 20131121 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.jpba.2004.08.034 |
| PMID: | 15533679 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0731-7085 |
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| DOI: | 10.1016/j.jpba.2004.08.034 |