دورية أكاديمية
Complications of gastrectomy with lymphadenectomy in gastric cancer.
العنوان: | Complications of gastrectomy with lymphadenectomy in gastric cancer. |
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المؤلفون: | Zilberstein B; Department of Gastroenterology, University of São Paulo School of Medicine, Av 9 de Julho 4440, São Paulo, SP, 01406-100, Brazil., Martins BC, Jacob CE, Bresciani C, Lopasso FP, de Cleva R, Pinto Junior PE, Junior UR, Perez RO, Gama-Rodrigues J |
المصدر: | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association [Gastric Cancer] 2004; Vol. 7 (4), pp. 254-9. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer-Verlag Tokyo Country of Publication: Japan NLM ID: 100886238 Publication Model: Print Cited Medium: Print ISSN: 1436-3291 (Print) Linking ISSN: 14363291 NLM ISO Abbreviation: Gastric Cancer Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Tokyo : Springer-Verlag Tokyo, c1998- |
مواضيع طبية MeSH: | Postoperative Complications*, Adenocarcinoma/*surgery , Gastrectomy/*adverse effects , Lymph Node Excision/*adverse effects , Stomach Neoplasms/*surgery, Adenocarcinoma/pathology ; Adult ; Aged ; Aged, 80 and over ; Female ; Gastrectomy/mortality ; Humans ; Japan ; Lymph Node Excision/mortality ; Male ; Middle Aged ; Retrospective Studies ; Stomach Neoplasms/pathology |
مستخلص: | Background: Currently, gastrectomy and extended lymphadenectomy (LN) is the treatment of choice for gastric cancer. Although a survival rate benefit of D2 LN compared to D1 LN has been shown, the D2 LN procedure is not fully employed, due to possible higher morbidity and mortality rates. These higher rates are being questioned in more recent series, in which D1 and D2 LN complication rates have been similar. The aim of this study was to analyze the immediate postoperative complications of patients submitted to total or subtotal gastrectomy with D1 or D2 LN (according to the Japanese guidelines for gastric cancer) at the Gastrointestinal Surgery Division of the Medical School of São Paulo University, between January 2001 and April 2003. Methods: One hundred consecutive patients were studied; 61 were men and 39, women. Total gastrectomy was performed in 52 patients (13 with D1 LN and 39 with D2 LN), and subtotal gastrectomy was performed in 48 (11 with D1 LN and 37 with D2 LN). Total or subtotal gastrectomy with D1 or D2 LN was performed according to the tumor extent and histological classification (Lauren's diffuse or intestinal type), considering the patient's general condition and the gastric cancer stage. Roux-en-Y reconstruction was performed in almost all patients. Results: No difference was observed regarding complications and mortality related to the extent of the gastrectomy. Although morbidity was higher in the D1 group, no significant difference was observed. Mortality was higher in the D1 group, and this was probably related to their poor surgical condition and more advanced tumors. Conclusion: According to these results, it appears that total or subtotal gastrectomy with D2 LN in gastric cancer treatment, performed according to the Japanese guidelines, can be considered a safe procedure, with acceptable morbidity and mortality, when performed by a trained surgical team. |
تواريخ الأحداث: | Date Created: 20041224 Date Completed: 20050315 Latest Revision: 20160512 |
رمز التحديث: | 20221213 |
DOI: | 10.1007/s10120-004-0301-8 |
PMID: | 15616774 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1436-3291 |
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DOI: | 10.1007/s10120-004-0301-8 |