التفاصيل البيبلوغرافية
| العنوان: |
[Absence of hypolipidemic effect of Solanum melongena L. (eggplant) on hyperlipidemic patients]. |
| عنوان ترانسليتريتد: |
Ausência de efeito hipolipemiante da Solanum melongena L. (berinjela) em pacientes hiperlipidêmicos. |
| المؤلفون: |
Silva GE; Departamento de Farmácia e Farmacologia, Universidade Estadual de Maringá, Maringá, PR., Takahashi MH, Eik Filho W, Albino CC, Tasim GE, Serri Lde A, Assef AH, Cortez DA, Bazotte RB |
| المصدر: |
Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2004 Jun; Vol. 48 (3), pp. 368-73. Date of Electronic Publication: 2004 Aug 26. |
| نوع المنشور: |
Clinical Trial; English Abstract; Journal Article; Randomized Controlled Trial |
| اللغة: |
Portuguese |
| بيانات الدورية: |
Publisher: Sociedade Brasileira de Endocrinologia e Metabologia Country of Publication: Brazil NLM ID: 0403437 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0004-2730 (Print) Linking ISSN: 00042730 NLM ISO Abbreviation: Arq Bras Endocrinol Metabol Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Rio de Janeiro : Sociedade Brasileira de Endocrinologia e Metabologia |
| مواضيع طبية MeSH: |
Fruit* , Phytotherapy* , Solanum melongena*, Hyperlipidemias/*drug therapy , Plant Extracts/*therapeutic use, Double-Blind Method ; Humans ; Longitudinal Studies ; Middle Aged |
| مستخلص: |
In this study we investigated the hypolipidemic potential of dried powdered fruits of eggplant (Solanum melongena), which has been commercialized in Brazil to treat human hyperlipidemia. Thus, a double-blind placebo-controlled study of the effectiveness of oral Solanum melongena (SM) was conducted. The study consisted of 41 hyperlipidemic volunteers allocated to active treatment (n= 21) or placebo (n= 20). Each volunteer received two capsules containing SM (450 mg) or placebo (450 mg) twice daily and were followed monthly. The dose of SM used corresponds to that given to treat hyperlipidemia in Brazil. After 3 months, serum total cholesterol, LDL-c and LDL-c/HDL-c decreased (p<0.05) in the group treated with SM. However similar effect was also observed in the placebo group. The other parameters, including serum triglycerides, HDL-c, VLDL-c, AST, ALT, gGT, glucose and body mass index, showed no significant changes. We conclude that SM, at least in the form commercialized in the Brazil (dried powdered fruits), require further clinical trials before being recommended to treat hyperlipidemia. |
| المشرفين على المادة: |
0 (Plant Extracts) |
| تواريخ الأحداث: |
Date Created: 20050111 Date Completed: 20050503 Latest Revision: 20190917 |
| رمز التحديث: |
20240628 |
| DOI: |
10.1590/s0004-27302004000300006 |
| PMID: |
15640898 |
| قاعدة البيانات: |
MEDLINE |
