دورية أكاديمية
[The role of orlistat in the treatment of obesity].
| العنوان: | [The role of orlistat in the treatment of obesity]. |
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| عنوان ترانسليتريتد: | Az orlistat szerepe az elhízás kezelésében. |
| المؤلفون: | Paragh G; Debreceni Egyetem Orvos- és Egészségtudományi Centrum, Altalános Orvostudományi Kar, I. Belgyógyászati Klinika., Bajnok L |
| المصدر: | Orvosi hetilap [Orv Hetil] 2005 Mar 13; Vol. 146 (11), pp. 493-8. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | Hungarian |
| بيانات الدورية: | Publisher: Akademiai Kiado Country of Publication: Hungary NLM ID: 0376412 Publication Model: Print Cited Medium: Print ISSN: 0030-6002 (Print) Linking ISSN: 00306002 NLM ISO Abbreviation: Orv Hetil Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2007- : Budapest : Akademiai Kiado Original Publication: Pest : Markusovszky Lajos |
| مواضيع طبية MeSH: | Anti-Obesity Agents/*therapeutic use , Intestinal Absorption/*drug effects , Lactones/*therapeutic use , Lipase/*antagonists & inhibitors , Obesity/*drug therapy, Anti-Obesity Agents/adverse effects ; Humans ; Lactones/adverse effects ; Obesity/complications ; Obesity/therapy ; Orlistat ; Pancrelipase/antagonists & inhibitors |
| مستخلص: | The overweight and obesity represent severe problems for the health management system of developed countries. In the evolution of obesity, beside genetic background, the environmental factors also play important roles. In the daily routine, the majority of obese patients need drug treatment, over the diet and physical activity. Among the available medicines the inhibitors of monoamine re-uptake causes dry mouth, tachycardia, sleeplessness and elevated blood pressure, therefore, due to the frequently associated obesity and hypertension many physicians avoid using these compounds. The orlistat as a selective inhibitor of pancreatic and enteral lipase enzymes impedes the absorption of the highest calorie containing nutrients, the fats exerting beneficial effects in the treatment of obesity. The abdominal bloating and diarrhea as side effects of the drug may act as an advantage in many cases, since these happen especially in those cases when the patient neglects the previously suggested low fat diet and therefore the drug induced diarrhea and bloating may mean a feed-back for the patient in respect of the proper diet. Recent studies show many beneficial biochemical changes in obesity related pathological metabolic processes during the administration of orlistat. The authors, in their present work review in short the role of orlistat in the treatment of slimming cure. |
| Number of References: | 47 |
| المشرفين على المادة: | 0 (Anti-Obesity Agents) 0 (Lactones) 53608-75-6 (Pancrelipase) 95M8R751W8 (Orlistat) EC 3.1.1.3 (Lipase) |
| تواريخ الأحداث: | Date Created: 20050409 Date Completed: 20050426 Latest Revision: 20181201 |
| رمز التحديث: | 20231215 |
| PMID: | 15813187 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0030-6002 |
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