دورية أكاديمية

[Effect of polymer concentration on rheological properties of Carbopol 980 hydrogels containing trimecainium chloride].

التفاصيل البيبلوغرافية
العنوان: [Effect of polymer concentration on rheological properties of Carbopol 980 hydrogels containing trimecainium chloride].
عنوان ترانسليتريتد: Vplyv koncentrácie polyméru na reologické vlastnosti hydrogélov Carbopolu 980 s obsahom trimekaíniumchloridu.
المؤلفون: Subová M; Farmaceutická fakulta Univerzity Komenského v Bratislave, Katedra galenickej farmácie. margareta@centrum.sk, Vitková Z, Cirbusová E, Erös I, Kónya M
المصدر: Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti [Ceska Slov Farm] 2005 Mar; Vol. 54 (2), pp. 96-9.
نوع المنشور: Journal Article
اللغة: Slovak
بيانات الدورية: Publisher: Ceská lékarská spolecnost J. E. Purkyne Country of Publication: Czech Republic NLM ID: 9433765 Publication Model: Print Cited Medium: Print ISSN: 1210-7816 (Print) Linking ISSN: 12107816 NLM ISO Abbreviation: Ceska Slov Farm Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Praha : Ceská lékarská spolecnost J. E. Purkyne,
مواضيع طبية MeSH: Anesthetics, Local* , Trimecaine*, Acrylic Resins/*chemistry , Hydrogels/*chemistry, Chemical Phenomena ; Chemistry, Physical ; Rheology
مستخلص: Rheological properties exert influence on the manufacturing processes, stability and usability of a dosage form as well as the biological availability of an active ingredient. The present paper examines the effect of Carbopol 980 concentration on rheological properties of hydrogels with and without trimecainium chloride for a period of 2, 7, and 14 days after their preparation. On the basis of an evaluation of the changes in structural viscosity in dependence on the period of measurement, it has been concluded that for formulation of trimecainium chloride to a dermal dosage form, Carbopol 980 concentrations of 0.5 and 1.2 % are suitable.
المشرفين على المادة: 0 (Acrylic Resins)
0 (Anesthetics, Local)
0 (Hydrogels)
0 (carbomer)
IN1233R0JO (Trimecaine)
تواريخ الأحداث: Date Created: 20050518 Date Completed: 20050614 Latest Revision: 20161124
رمز التحديث: 20231215
PMID: 15895974
قاعدة البيانات: MEDLINE