دورية أكاديمية
Hyperemesis gravidarum, a literature review.
| العنوان: | Hyperemesis gravidarum, a literature review. |
|---|---|
| المؤلفون: | Verberg MF; Academic Unit of Reproductive Physiology, Obstetrics and Gynaecology, St. Bartholomew's Hospital, West Smithfield, London, UK., Gillott DJ, Al-Fardan N, Grudzinskas JG |
| المصدر: | Human reproduction update [Hum Reprod Update] 2005 Sep-Oct; Vol. 11 (5), pp. 527-39. Date of Electronic Publication: 2005 Jul 08. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published for the European Society of Human Reproduction and Embryology by Oxford University Press Country of Publication: England NLM ID: 9507614 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1355-4786 (Print) Linking ISSN: 13554786 NLM ISO Abbreviation: Hum Reprod Update Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford, UK : Published for the European Society of Human Reproduction and Embryology by Oxford University Press, c1995- |
| مواضيع طبية MeSH: | Hyperemesis Gravidarum/*etiology, Adrenal Cortex/metabolism ; Chorionic Gonadotropin/blood ; Enzymes/metabolism ; Esophageal Sphincter, Lower/metabolism ; Estrogens/blood ; Female ; Helicobacter Infections/blood ; Helicobacter pylori ; Human Growth Hormone/metabolism ; Humans ; Hyperemesis Gravidarum/immunology ; Hyperemesis Gravidarum/psychology ; Hyperemesis Gravidarum/therapy ; Leptin/blood ; Placenta/metabolism ; Pregnancy ; Progesterone/blood ; Prolactin/blood ; Thyroid Hormones/blood ; Trace Elements/deficiency |
| مستخلص: | Hyperemesis gravidarum (HG) is a condition causing severe nausea and vomiting in early pregnancy often resulting in hospital admission. The incidence of HG is approximately 0.5% of live births, said to be higher in multiple pregnancies, hydatidiform mole and other conditions associated with increased pregnancy hormone levels. Both the aetiology and pathogenesis of HG remain unknown. We conducted a literature review (1966-now) to summarize the current evidence on the aetiology and pathogenesis of HG. The potential role of pregnancy-related hormones such as progesterone, estrogen and HCG has been widely studied; however, various other hormones such as leptin, placental growth hormone, prolactin, thyroid and adrenal cortical hormones have been implicated in the aetiology of HG. In addition to endocrinological hypotheses, the rationale and evidence considering infectious, immunological, psychological, metabolic and anatomical causes for HG have been analysed here. Many studies suffer from the low number of patients included, the variable definition used for HG and varying assay methodology used in studies of hormone measurement. This review highlights the need for more extensive studies addressing the pathogenesis and aetiology of HG. |
| Number of References: | 175 |
| التعليقات: | Erratum in: Hum Reprod Update. 2007 Mar-Apr;13(2):207. |
| المشرفين على المادة: | 0 (Chorionic Gonadotropin) 0 (Enzymes) 0 (Estrogens) 0 (Leptin) 0 (Thyroid Hormones) 0 (Trace Elements) 12629-01-5 (Human Growth Hormone) 4G7DS2Q64Y (Progesterone) 9002-62-4 (Prolactin) |
| تواريخ الأحداث: | Date Created: 20050712 Date Completed: 20051107 Latest Revision: 20220310 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1093/humupd/dmi021 |
| PMID: | 16006438 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1355-4786 |
|---|---|
| DOI: | 10.1093/humupd/dmi021 |