دورية أكاديمية
Thiopental vs. etomidate for rapid sequence intubation in aeromedicine.
| العنوان: | Thiopental vs. etomidate for rapid sequence intubation in aeromedicine. |
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| المؤلفون: | Sonday CJ; University of Pennsylvania, Philadelphia, Pennsylvania, USA., Axelband J, Jacoby J, Higgins R, Crider D |
| المصدر: | Prehospital and disaster medicine [Prehosp Disaster Med] 2005 Sep-Oct; Vol. 20 (5), pp. 324-6. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cambridge University Press Country of Publication: United States NLM ID: 8918173 Publication Model: Print Cited Medium: Print ISSN: 1049-023X (Print) Linking ISSN: 1049023X NLM ISO Abbreviation: Prehosp Disaster Med |
| أسماء مطبوعة: | Publication: 2011- : New York : Cambridge University Press Original Publication: [Solana Beach, CA] : Jems Pub. Co., [c1989]- |
| مواضيع طبية MeSH: | Air Ambulances*/statistics & numerical data, Etomidate/*therapeutic use , Hypnotics and Sedatives/*therapeutic use , Intubation, Intratracheal/*instrumentation , Intubation, Intratracheal/*methods , Thiopental/*therapeutic use, Adolescent ; Adult ; Aged ; Allied Health Personnel ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Emergency Nursing/methods ; Female ; Humans ; Intubation, Intratracheal/statistics & numerical data ; Male ; Middle Aged ; Neuromuscular Depolarizing Agents/therapeutic use ; Outcome and Process Assessment, Health Care ; Pennsylvania ; Retrospective Studies ; Succinylcholine/therapeutic use ; Treatment Outcome |
| مستخلص: | Introduction: Although there is a general agreement that rapid sequence intubation (RSI) is the preferred technique for intubation in aeromedical care, several pharamacological regimens have been employed without clear evidence of which is superior. Hypothesis: This study was designed to compare the use of etomidate (ETOM) with that of thiopental (THIO) as an adjunctive agent used with succinylcholine (SCh) for RSI in an urban, aeromedical system. Methods: This was a retrospective, before-and-after study utilizing computer-assisted chart review. Adult patients who received THIO for RSI over a two-year period were compared to adult patients who received ETOM for RSI over a similar period, after a change in protocol, which mandated ETOM rather than THIO for all intubations. Results: No difference was found in any of the primary endpoints. Stabilization time (13.1 vs. 12.9 minutes), number of intubation attempts (1.1 vs. 1.2), successful first intubation attempts (90% vs. 82%), overall successful intubations (100% vs. 96%), and intubation time (18.4 vs. 21.7 seconds) were similar for all comparisons of THIO vs. ETOM (all p > 0.05). Conclusion: This study found no clinically relevant differences between the use of ETOM or THIO as adjuncts with SCh for RSI in the aeromedical setting. |
| المشرفين على المادة: | 0 (Hypnotics and Sedatives) 0 (Neuromuscular Depolarizing Agents) J2R869A8YF (Succinylcholine) JI8Z5M7NA3 (Thiopental) Z22628B598 (Etomidate) |
| تواريخ الأحداث: | Date Created: 20051122 Date Completed: 20060209 Latest Revision: 20191210 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1017/s1049023x00002788 |
| PMID: | 16295169 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1049-023X |
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| DOI: | 10.1017/s1049023x00002788 |