دورية أكاديمية
أعرض في EDS

Advantages of new cardiovascular risk-assessment strategies in high-risk patients with hypertension.

التفاصيل البيبلوغرافية
العنوان: Advantages of new cardiovascular risk-assessment strategies in high-risk patients with hypertension.
المؤلفون: Ruilope LM; Hypertension Unit, Hospital 12 de Octubre, Madrid, Spain. ruilipe@ad-hocbox.com, Segura J
المصدر: Clinical therapeutics [Clin Ther] 2005 Oct; Vol. 27 (10), pp. 1658-68.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print Cited Medium: Print ISSN: 0149-2918 (Print) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE
أسماء مطبوعة: Publication: 1998- : Belle Mead, NJ, : Excerpta Medica
Original Publication: Princeton, N. J., Excerpta Medica.
مواضيع طبية MeSH: Cardiovascular Diseases/*prevention & control , Hypertension/*prevention & control, Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/therapy ; Humans ; Hypertension/diagnosis ; Hypertension/therapy ; Practice Guidelines as Topic ; Risk Assessment/methods
مستخلص: Background: Accurate assessment of cardiovascular disease (CVD) risk in patients with hypertension is important when planning appropriate treatment of modifiable risk factors. The causes of CVD are multifactorial, and hypertension seldom exists as an isolated risk factor. Classic models of risk assessment are more accurate than a simple counting of risk factors, but they are not generalizable to all populations. In addition, the risk associated with hypertension is graded, continuous, and independent of other risk factors, and this is not reflected in classic models of risk assessment.
Objective: This article is intended to review both classic and newer models of CVD risk assessment.
Methods: MEDLINE was searched for articles published between 1990 and 2005 that contained the terms cardiovascular disease, hypertension, or risk assessment. Articles describing major clinical trials, new data about cardiovascular risk, or global risk stratification were selected for review.
Results: Some patients at high long-term risk for CVD events (eg, patients aged <50 years with multiple risk factors) may go untreated because they do not meet the absolute risk-intervention threshold of 20% risk over 10 years with the classic model. Recognition of the limitations of classic risk-assessment models led to new guidelines, particularly those of the European Society of Hypertension-European Society of Cardiology. These guidelines view hypertension as one of many risk and disease factors that require treatment to decrease risk. These newer guidelines include a more comprehensive range of risk factors and more finely graded blood pressure ranges to stratify patients by degree of risk. Whether they accurately predict CVD risk in most populations is not known. Evidence from the Valsartan Antihypertensive Long-term Use Evaluation (VALUE) study, which stratified patients by several risk and disease factors, highlights the predictive value of some newer CVD risk assessments.
Conclusion: Modern risk assessments, which include blood pressure along with a wide array of modifiable risk factors, may be more accurate than classic models for CVD risk prediction.
Number of References: 48
تواريخ الأحداث: Date Created: 20051207 Date Completed: 20060201 Latest Revision: 20071115
رمز التحديث: 20221213
DOI: 10.1016/j.clinthera.2005.10.013
PMID: 16330303
قاعدة البيانات: MEDLINE
الوصف
تدمد:0149-2918
DOI:10.1016/j.clinthera.2005.10.013