دورية أكاديمية
Aluminum in tobacco and cannabis and smoking-related disease.
| العنوان: | Aluminum in tobacco and cannabis and smoking-related disease. |
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| المؤلفون: | Exley C; Birchall Centre for Inorganic Chemistry and Materials Science, Keele University, Staffordshire, United Kingdom. c.exley@chem.keele.ac.uk, Begum A, Woolley MP, Bloor RN |
| المصدر: | The American journal of medicine [Am J Med] 2006 Mar; Vol. 119 (3), pp. 276.e9-11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Excerpta Medica Country of Publication: United States NLM ID: 0267200 Publication Model: Print Cited Medium: Internet ISSN: 1555-7162 (Electronic) Linking ISSN: 00029343 NLM ISO Abbreviation: Am J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, NY : Excerpta Medica Original Publication: New York, Donnelly. |
| مواضيع طبية MeSH: | Aluminum/*analysis , Cannabis/*chemistry , Nicotiana/*chemistry, Aluminum/adverse effects ; Aluminum/pharmacokinetics ; Biological Availability ; Humans ; Lung/metabolism ; Lung Diseases/chemically induced |
| مستخلص: | Purpose: The study aimed to confirm the very high content of aluminum in tobacco and cannabis and to provide for the first time evidence that such aluminum could be biologically available. Methods: Complete digestion of tobacco and cannabis was achieved using a 50:50 mixture of 14 M HNO3 and 0.1 M NaF. Total Al in digests was measured by graphite furnace atomic absorption spectrometry. A bespoke cigarette smoking apparatus was used to determine if aluminum in active or passive tobacco/cannabis smoke would be trapped by a surrogate lung fluid. Results: The aluminum content of tobacco and cannabis was confirmed to be high, as much as 0.37% and 0.4% by weight respectively. Aluminum in tobacco and cannabis smoke, whether actively (drawn) or passively inhaled, was shown to accumulate significantly in surrogate lung fluids, thus demonstrating its potential biological availability. Conclusions: Active and passive smoking of tobacco or cannabis will increase the body burden of aluminum and thereby contribute to respiratory, neurological and other smoking-related disease. |
| المشرفين على المادة: | CPD4NFA903 (Aluminum) |
| تواريخ الأحداث: | Date Created: 20060224 Date Completed: 20060302 Latest Revision: 20231213 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.amjmed.2005.08.004 |
| PMID: | 16490479 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1555-7162 |
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| DOI: | 10.1016/j.amjmed.2005.08.004 |