دورية أكاديمية
[Study of paroxysmal kinesigenic dyskinesia with fMRI].
| العنوان: | [Study of paroxysmal kinesigenic dyskinesia with fMRI]. |
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| المؤلفون: | Zhu YH; College of Medicine, Zhejiang University, Hangzhou 310006, China. rhzhu@hzcnc.com, Luo BY, Ruan LX, Wang MH, Li JC, Weng XC, Chen YZ |
| المصدر: | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences [Zhejiang Da Xue Xue Bao Yi Xue Ban] 2006 Mar; Vol. 35 (2), pp. 189-93. |
| نوع المنشور: | English Abstract; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Zhejiang da xue xue bao bian ji bu Country of Publication: China NLM ID: 100927946 Publication Model: Print Cited Medium: Print ISSN: 1008-9292 (Print) Linking ISSN: 10089292 NLM ISO Abbreviation: Zhejiang Da Xue Xue Bao Yi Xue Ban Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hangzhou : Zhejiang da xue xue bao bian ji bu, [1999]- |
| مواضيع طبية MeSH: | Magnetic Resonance Imaging*, Chorea/*physiopathology , Motor Cortex/*physiopathology , Movement/*physiology, Adult ; Humans ; Male |
| مستخلص: | Objective: To detect the differences in subcortical structures between patients with paroxysmal kinesigenic dyskinesia (PKD) and normal subjects during movement preparation and execution. Methods: The PKD patients performed a movement task, in which a CUE signal (preparation) indicated the movement sequence prior to the appearance of an imperative GO signal (execution). Event-related functional magnetic resonance imaging (fMRI) and 3dDeconvolve program of AFNI were used to estimate the hemodynamic response function and to generate activation maps. Result: During movement preparation, the activated brain areas in PKD patients were less than those of normal subject, and there was no activation in basal ganglia in PKD patients. During execution, the activation was also less in PKD patients except in bilateral M1. Conclusion: During intermission, abnormalities of the brain still exist in PKD patients when during preparing or performing movement. The movement circuit in the brain displays an unusual state. The attack may be caused by reducing of inhibition in brain areas. |
| تواريخ الأحداث: | Date Created: 20060413 Date Completed: 20061130 Latest Revision: 20220327 |
| رمز التحديث: | 20240829 |
| DOI: | 10.3785/j.issn.1008-9292.2006.02.014 |
| PMID: | 16610087 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1008-9292 |
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| DOI: | 10.3785/j.issn.1008-9292.2006.02.014 |