دورية أكاديمية
Effects of Lactobacillus acidophilus DSM13241 as a probiotic in healthy adult cats.
| العنوان: | Effects of Lactobacillus acidophilus DSM13241 as a probiotic in healthy adult cats. |
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| المؤلفون: | Marshall-Jones ZV; Waltham Centre for Pet Nutrition, Waltham-on-the-Wolds, Melton Mowbray, Leicestershire, LE14 4RT, UK., Baillon ML, Croft JM, Butterwick RF |
| المصدر: | American journal of veterinary research [Am J Vet Res] 2006 Jun; Vol. 67 (6), pp. 1005-12. |
| نوع المنشور: | Controlled Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Veterinary Medical Association Country of Publication: United States NLM ID: 0375011 Publication Model: Print Cited Medium: Print ISSN: 0002-9645 (Print) Linking ISSN: 00029645 NLM ISO Abbreviation: Am J Vet Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Schaumburg, Ill. : American Veterinary Medical Association Original Publication: Chicago : American Veterinary Medical Assn. |
| مواضيع طبية MeSH: | Cats* , Health*, Lactobacillus acidophilus/*metabolism , Probiotics/*pharmacology, Animal Feed ; Animal Nutritional Physiological Phenomena ; Animals ; Cross-Over Studies ; Diet/veterinary ; Dietary Supplements ; Feces |
| مستخلص: | Objective: To evaluate the effect of dietary supplementation with the probiotic strain Lactobacillus acidophilus DSM13241 in healthy adult cats. Animals: 15 adult cats. Procedures: Cats were fed a nutritionally complete dry food for 5 weeks. Fecal character was assessed daily, and a single fecal sample and 3-mL blood sample were collected for bacterial enumeration and hematologic analysis, respectively. Cats were then fed the same diet supplemented with L acidophilus DSM13241 (2 x 10(8) CFU/d) for 4.5 weeks. Repeat fecal and hematologic measurements were taken prior to the return to control diet for a 4-week period. Results: The probiotic species was recovered from feces, demonstrating survival through the feline gastrointestinal tract. Probiotic supplementation was associated with increased numbers of beneficial Lactobacillus and L acidophilus groups in feces and decreased numbers of Clostridium spp and Enterococcus faecalis, indicating an altered bacterial balance in the gastrointestinal tract microflora. Fecal pH was also decreased suggesting a colonic environment selective for the beneficial lactic acid bacterial population. Systemic and immunomodulatory effects were associated with administration of L acidophilus DSM13241 including altered cell numbers within WBC subsets and enhanced phagocytic capacity in the peripheral granulocyte population. In addition, plasma endotoxin concentrations were decreased during probiotic feeding, and RBCs had a decreased susceptibility to osmotic pressure. Conclusions and Clinical Relevance: Probiotic strain L acidophilus DSM13241 fed at 2 x 10(8) CFU/d can alter the balance of gastrointestinal microflora in healthy cats. Furthermore, administration of this probiotic results in beneficial systemic and immunomodulatory effects in cats. |
| تواريخ الأحداث: | Date Created: 20060603 Date Completed: 20070411 Latest Revision: 20220318 |
| رمز التحديث: | 20231215 |
| DOI: | 10.2460/ajvr.67.6.1005 |
| PMID: | 16740094 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0002-9645 |
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| DOI: | 10.2460/ajvr.67.6.1005 |