دورية أكاديمية
Colonic involvement in Stevens-Johnson syndrome.
العنوان: | Colonic involvement in Stevens-Johnson syndrome. |
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المؤلفون: | Powell N; Department of Gastroenterology, Queen Elizabeth Hospital, London, UK. nick.powell@nhs.net, Munro JM, Rowbotham D |
المصدر: | Postgraduate medical journal [Postgrad Med J] 2006 Jun; Vol. 82 (968), pp. e10. |
نوع المنشور: | Case Reports; Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0234135 Publication Model: Print Cited Medium: Internet ISSN: 1469-0756 (Electronic) Linking ISSN: 00325473 NLM ISO Abbreviation: Postgrad Med J Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2023- : Oxford : Oxford University Press Original Publication: London, Blackwell. |
مواضيع طبية MeSH: | Anticonvulsants/*adverse effects , Colitis/*chemically induced , Diarrhea/*chemically induced , Malnutrition/*chemically induced , Phenytoin/*adverse effects , Stevens-Johnson Syndrome/*chemically induced, Adolescent ; Epilepsy, Tonic-Clonic/drug therapy ; Humans ; Male |
مستخلص: | Severe gastrointestinal tract involvement is a rare manifestation of Stevens-Johnson syndrome (SJS). The case is described of a 17 year old man who developed SJS secondary to phenytoin. In addition to the cutaneous, ocular, and oral mucosal lesions typical of SJS, he also developed persistent, bloody diarrhoea associated with life threatening malnutrition. Serial colonoscopy showed severe and progressive colitis. He was treated with a combination of long term nutritional support, probiotic therapy, and supportive measures. He was eventually discharged from hospital six months after admission when the diarrhoea improved and he began to gain weight. |
References: | Allergy Asthma Proc. 2000 Mar-Apr;21(2):101-5. (PMID: 10791111) Endoscopy. 2001 Jun;33(6):550-3. (PMID: 11437052) Dig Dis Sci. 2001 Nov;46(11):2385-8. (PMID: 11713940) Curr Opin Allergy Clin Immunol. 2001 Aug;1(4):293-8. (PMID: 11964703) Arch Dermatol. 2002 Aug;138(8):1019-24. (PMID: 12164739) Pediatrics. 2003 Dec;112(6 Pt 1):1430-6. (PMID: 14654625) Immunol Rev. 2005 Apr;204:144-55. (PMID: 15790356) Gastroenterology. 1985 Jun;88(6):1954-7. (PMID: 3873374) Gastroenterology. 1986 Aug;91(2):469-74. (PMID: 3721130) Int J Cancer. 1994 May 1;57(3):371-7. (PMID: 8168998) Gastroenterology. 1998 Sep;115(3):743-6. (PMID: 9721172) Science. 1998 Oct 16;282(5388):490-3. (PMID: 9774279) Gut. 2005 Feb;54(2):242-9. (PMID: 15647189) Clin Exp Dermatol. 1979 Jun;4(2):201-4. (PMID: 159145) |
المشرفين على المادة: | 0 (Anticonvulsants) 6158TKW0C5 (Phenytoin) |
تواريخ الأحداث: | Date Created: 20060607 Date Completed: 20061127 Latest Revision: 20181113 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC2563745 |
DOI: | 10.1136/pgmj.2005.042952 |
PMID: | 16754699 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1469-0756 |
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DOI: | 10.1136/pgmj.2005.042952 |