دورية أكاديمية

Colonic involvement in Stevens-Johnson syndrome.

التفاصيل البيبلوغرافية
العنوان: Colonic involvement in Stevens-Johnson syndrome.
المؤلفون: Powell N; Department of Gastroenterology, Queen Elizabeth Hospital, London, UK. nick.powell@nhs.net, Munro JM, Rowbotham D
المصدر: Postgraduate medical journal [Postgrad Med J] 2006 Jun; Vol. 82 (968), pp. e10.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0234135 Publication Model: Print Cited Medium: Internet ISSN: 1469-0756 (Electronic) Linking ISSN: 00325473 NLM ISO Abbreviation: Postgrad Med J Subsets: MEDLINE
أسماء مطبوعة: Publication: 2023- : Oxford : Oxford University Press
Original Publication: London, Blackwell.
مواضيع طبية MeSH: Anticonvulsants/*adverse effects , Colitis/*chemically induced , Diarrhea/*chemically induced , Malnutrition/*chemically induced , Phenytoin/*adverse effects , Stevens-Johnson Syndrome/*chemically induced, Adolescent ; Epilepsy, Tonic-Clonic/drug therapy ; Humans ; Male
مستخلص: Severe gastrointestinal tract involvement is a rare manifestation of Stevens-Johnson syndrome (SJS). The case is described of a 17 year old man who developed SJS secondary to phenytoin. In addition to the cutaneous, ocular, and oral mucosal lesions typical of SJS, he also developed persistent, bloody diarrhoea associated with life threatening malnutrition. Serial colonoscopy showed severe and progressive colitis. He was treated with a combination of long term nutritional support, probiotic therapy, and supportive measures. He was eventually discharged from hospital six months after admission when the diarrhoea improved and he began to gain weight.
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المشرفين على المادة: 0 (Anticonvulsants)
6158TKW0C5 (Phenytoin)
تواريخ الأحداث: Date Created: 20060607 Date Completed: 20061127 Latest Revision: 20181113
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC2563745
DOI: 10.1136/pgmj.2005.042952
PMID: 16754699
قاعدة البيانات: MEDLINE
الوصف
تدمد:1469-0756
DOI:10.1136/pgmj.2005.042952