دورية أكاديمية

[Genetic monitoring of the Crimean-Congo Hemorrhagic Fever virus in Kazakhstan and Tajikistan in 2001-2003].

التفاصيل البيبلوغرافية
العنوان: [Genetic monitoring of the Crimean-Congo Hemorrhagic Fever virus in Kazakhstan and Tajikistan in 2001-2003].
المؤلفون: Tumanova IIu, Seregin SV, Vyshemirskiĭ OI, Gutorov VV, Petrova ID, Tiunnikov GI, Ospanov KS, Kazakov SV, Karimov S, Tishkova FKh, Pirov AI, Netesov SV, Petrov VS
المصدر: Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 2006 (2), pp. 36-41.
نوع المنشور: English Abstract; Journal Article
اللغة: Russian
بيانات الدورية: Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 9315607 Publication Model: Print Cited Medium: Print ISSN: 0208-0613 (Print) Linking ISSN: 02080613 NLM ISO Abbreviation: Mol Gen Mikrobiol Virusol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Moskva : Meditsina,
مواضيع طبية MeSH: Disease Outbreaks* , Genetic Variation*, Hemorrhagic Fever Virus, Crimean-Congo/*classification , Hemorrhagic Fever Virus, Crimean-Congo/*genetics , Hemorrhagic Fever, Crimean/*epidemiology , RNA, Viral/*analysis, Animals ; Base Sequence ; Environmental Monitoring ; Epidemiological Monitoring ; Hemorrhagic Fever Virus, Crimean-Congo/isolation & purification ; Hemorrhagic Fever, Crimean/microbiology ; Humans ; Ixodidae/virology ; Kazakhstan/epidemiology ; Molecular Sequence Data ; Phylogeny ; RNA, Viral/blood ; RNA, Viral/genetics ; Tajikistan/epidemiology
مستخلص: Blood specimens obtained from 32 CCHF patients were tested for the presence of CCHF virus markers. In addition, 3210 ticks of the genera Hyalomma asiaticum, Hyalomma anatolicum, and Dermacentor niveus were examined to identify the CCHF virus antigen and RNA. This material was obtained during the 2001-2003 local outbreaks of CCHF in Kazakhstan and Tajikistan. The nucleotide sequence in the region 983-1282 of S segment of the CCHF virus for 12 wild type strains was determined. The phylogenetic relationships among the established biovariants of CCHF virus, and also between these biovariants and those from other regions of the world were identified. We were the first to demonstrate the presence of an African-like genotype of CCHF virus in the territory of Kazakhstan. The conclusion was made that two genotypes of CCHF virus were in circulation in Kazakhstan. It was also demonstrated that CCHF virus, circulating in the territories of Kazakhstan and Tajikistan, was genetically heterogeneous.
المشرفين على المادة: 0 (RNA, Viral)
تواريخ الأحداث: Date Created: 20060608 Date Completed: 20060712 Latest Revision: 20121115
رمز التحديث: 20240628
PMID: 16756002
قاعدة البيانات: MEDLINE