دورية أكاديمية
[The experimental anti-arrhythmia properties of the histamine H1 receptor blockader fencarol].
| العنوان: | [The experimental anti-arrhythmia properties of the histamine H1 receptor blockader fencarol]. |
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| عنوان ترانسليتريتد: | Antiaritmicheskie svoĭstva blokatora H1-gistaminovykh retseptorov fenkarola v éksperimente. |
| المؤلفون: | Iakovlev GM, Skorobogatov VI, Svistov AS, Mironova MI |
| المصدر: | Farmakologiia i toksikologiia [Farmakol Toksikol] 1991 Sep-Oct; Vol. 54 (5), pp. 25-7. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Izdatelstvo Meditsina Country of Publication: Russia (Federation) NLM ID: 16920420R Publication Model: Print Cited Medium: Print ISSN: 0014-8318 (Print) Linking ISSN: 00148318 NLM ISO Abbreviation: Farmakol Toksikol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Moscow : Izdatelstvo Meditsina |
| مواضيع طبية MeSH: | Anti-Arrhythmia Agents/*therapeutic use , Benzhydryl Compounds/*therapeutic use , Histamine H1 Antagonists/*therapeutic use, Animals ; Anti-Arrhythmia Agents/adverse effects ; Arrhythmias, Cardiac/chemically induced ; Arrhythmias, Cardiac/drug therapy ; Arrhythmias, Cardiac/physiopathology ; Benzhydryl Compounds/adverse effects ; Drug Evaluation, Preclinical ; Electrocardiography/drug effects ; Heart Rate/drug effects ; Histamine H1 Antagonists/adverse effects ; Male ; Rabbits |
| مستخلص: | Phencarol, a blocker of H1-histamine receptors, is used as an antihistaminic agent. The antiarrhythmic effect of phencarol was detected and studied on experimental models of arrhythmias in non-anesthetized rabbits in a dose of 5 mg/kg intravenously. The drug was shown to possess the pronounced antiarrhythmic and protective properties on the models of calcium-chloride-, adrenaline- and strophanthine-induced arrhythmias and to exert no influence on aconitine-induced arrhythmia. Phencarol was demonstrated to have no cardiodepressive effect. |
| المشرفين على المادة: | 0 (Anti-Arrhythmia Agents) 0 (Benzhydryl Compounds) 0 (Histamine H1 Antagonists) W9A18RJ49B (quifenadine) |
| تواريخ الأحداث: | Date Created: 19910901 Date Completed: 19920420 Latest Revision: 20121115 |
| رمز التحديث: | 20240627 |
| PMID: | 1686869 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0014-8318 |
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