دورية أكاديمية
[The genetic relation of four ethnic populations in China's Guizhou is revealed by sequence variations of mtDNA D-loop].
| العنوان: | [The genetic relation of four ethnic populations in China's Guizhou is revealed by sequence variations of mtDNA D-loop]. |
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| المؤلفون: | Li BB; Department of Pathophysiology, Guangdong Medical College, Zhanjiang, Guangdong 524023, P. R. China., Zhong FG, Yi HS, Wang XR, Li LF, Wang LL, Qi XL, Wu LF |
| المصدر: | Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2006 Aug; Vol. 23 (4), pp. 456-60. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | Chinese |
| بيانات الدورية: | Publisher: Sichuan University Country of Publication: China NLM ID: 9425197 Publication Model: Print Cited Medium: Print ISSN: 1003-9406 (Print) Linking ISSN: 10039406 NLM ISO Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Za Zhi Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2004->: Chengdu, Sichuan, P.R. China : Sichuan University Original Publication: Chengdu : Hua xi yi ke da xue, |
| مواضيع طبية MeSH: | Genetic Variation*, DNA, Mitochondrial/*genetics , Ethnicity/*genetics, Base Sequence ; China ; DNA, Mitochondrial/chemistry ; DNA, Mitochondrial/classification ; Humans ; Molecular Sequence Data ; Phylogeny ; Polymerase Chain Reaction ; Polymorphism, Genetic/genetics ; Sequence Analysis, DNA ; Sequence Homology, Nucleic Acid |
| مستخلص: | Objective: Through maternal inheritance, to explore the genetic structures and relationships of Dong, Gelao, Tujia and Yi ethnic population in Guizhou of China. Methods: The mtDNA D-loop hypervariable segment I (HVS I ) in 108 samples of four ethnic populations were sequenced. Then, the nucleotide diversity was estimated and a phylogenetic tree was constructed by Neighbor-Joining method. Results: In the detected 497 bp fragments, 86 polymorphic sites were found, and 82 different haplotypes were identified. The phylogenetic tree of four ethnic populations showed: Yi, Tujia and Gelao clustered more closely than Dong did. Conclusion: Yi and Tujia population are very closely related, the reason may be that they either originate from a common ancestry or frequently undergo the gene exchanges and admixtures. The genetic relationship between Tujia and Gelao population is nearer, perhaps because they have settled in the adjacent regions. Dong and Yi population show the farthest genetic relationship, this is probably due to their different historical origins and geographic segregation. |
| المشرفين على المادة: | 0 (DNA, Mitochondrial) |
| تواريخ الأحداث: | Date Created: 20060803 Date Completed: 20090327 Latest Revision: 20211203 |
| رمز التحديث: | 20240628 |
| PMID: | 16883541 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1003-9406 |
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