دورية أكاديمية

Ovarian choriocarcinoma: a difficult diagnosis of an unusual tumor and a review of the hook effect.

التفاصيل البيبلوغرافية
العنوان: Ovarian choriocarcinoma: a difficult diagnosis of an unusual tumor and a review of the hook effect.
المؤلفون: Wheeler CA; Department of Obstetrics and Gynecology, Tulane University School of Medicine, New Orleans, Louisiana., Davis S, Degefu S, Thorneycroft IH, O'Quinn AG
المصدر: Obstetrics and gynecology [Obstet Gynecol] 1990 Mar; Vol. 75 (3 Pt 2), pp. 547-9.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401101 Publication Model: Print Cited Medium: Print ISSN: 0029-7844 (Print) Linking ISSN: 00297844 NLM ISO Abbreviation: Obstet Gynecol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2004- : Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: New York.
مواضيع طبية MeSH: Choriocarcinoma/*diagnosis , Chorionic Gonadotropin/*blood , Ovarian Neoplasms/*diagnosis , Peptide Fragments/*blood, Adult ; Biomarkers, Tumor/blood ; Choriocarcinoma/pathology ; Chorionic Gonadotropin, beta Subunit, Human ; Diagnostic Errors ; Female ; Humans ; Ovarian Neoplasms/pathology ; Pregnancy ; Pregnancy, Ectopic/diagnosis ; Radioimmunoassay
مستخلص: Ovarian choriocarcinoma is difficult to diagnose in the reproductive-age patient. A case of nongestational ovarian choriocarcinoma is discussed which presented like a molar pregnancy initially. Because of falsely low beta-hCG values (283 mIU/L) caused by the high-dose "hook effect" in the double antibody immunoassay system, however, a diagnosis of ectopic pregnancy was entertained. At laparotomy, a large necrotic ovarian choriocarcinoma was found along with large theca lutein cysts. The hook effect may mislead the clinician, and it is important to recognize this effect to avoid misdiagnosis.
المشرفين على المادة: 0 (Biomarkers, Tumor)
0 (Chorionic Gonadotropin)
0 (Chorionic Gonadotropin, beta Subunit, Human)
0 (Peptide Fragments)
تواريخ الأحداث: Date Created: 19900301 Date Completed: 19900320 Latest Revision: 20151119
رمز التحديث: 20231215
PMID: 1689478
قاعدة البيانات: MEDLINE