دورية أكاديمية
Zinc and copper status in children with high family risk of premature cardiovascular disease.
| العنوان: | Zinc and copper status in children with high family risk of premature cardiovascular disease. |
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| المؤلفون: | Kelishadi R; Department of Pediatrics, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Alikhassy H, Amiri M |
| المصدر: | Annals of Saudi medicine [Ann Saudi Med] 2002 Sep-Nov; Vol. 22 (5-6), pp. 291-4. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: King Faisal Specialist Hospital and Research Centre Country of Publication: Saudi Arabia NLM ID: 8507355 Publication Model: Print Cited Medium: Print ISSN: 0256-4947 (Print) Linking ISSN: 02564947 NLM ISO Abbreviation: Ann Saudi Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2012- : Riyadh : King Faisal Specialist Hospital and Research Centre Original Publication: [Riyadh, Saudi Arabia : King Faisal Specialist Hospital and Research Center and King Saud University College of Medicine, c1985- |
| مستخلص: | Background: Zinc and copper are beneficial to health, growth and development, and also for the prevention of cardiovascular disease (CVD) with regards to improved dietary habits as a preliminary step in CVD prevention. This study was conducted among 2-18-year-old children with high family risk of premature CVD in comparison to controls. Subjects and Methods: One hundred randomly selected children whose parents had premature myocardial infarction were included in the study. The controls were 100 individuals randomly selected from the case group's neighbors and matched for age, sex, and socioeconomic status. A four-day food record questionnaire was used to assess zinc and copper intakes, and their serum levels were determined using Flame-Atomic Absorption Spectrophotometry. The data were analyzed by SPSS/Windows V6 software, using the Student's t and Mantel-Hanzel tests. Significance of differences was considered at P<0.05. Results: The daily zinc intake was significantly lower in the case than control group (6.89+/-2.97 vs. 8.30+/-2.45 mg, P=0.047). The mean serum zinc level was not significantly different between both groups (82.12+/-14.1 vs. 92.26+/-23.7 microg/dL, P>0.05). Zinc deficiency was more prevalent among the case in boys than their controls (58% vs. 18%, P=0.04). This difference was not significantly in girls (44% vs. 40%). The daily intake and serum level of copper were not significantly different between the case and control groups. No case of copper deficiency was found. The mean systolic blood pressure was not significantly different between the zinc-deficient and zinc-sufficient subjects. Although the mean diastolic blood pressure of the former was higher than the latter, there was no statistically significant difference. About 23.7% of all studied sample had mild-to-moderate degrees of failure to thrive, with significantly lower daily intake and serum zinc level than other subjects (5.14+/-1.06 mg, 82.09+/-12.74 microg/dL vs. 6.89+/-2.14 mg, 99.25+/-27.15 microg/dL, respectively, P<0.05). Conclusion: It is recommended that emphasis be placed on the consumption of food rich in zinc by children, especially those with high family risk of premature CVD. |
| تواريخ الأحداث: | Date Created: 20061206 Date Completed: 20070611 Latest Revision: 20190507 |
| رمز التحديث: | 20221213 |
| DOI: | 10.5144/0256-4947.2002.291 |
| PMID: | 17146244 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0256-4947 |
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| DOI: | 10.5144/0256-4947.2002.291 |