دورية أكاديمية
Effect of depression treatment on depressive symptoms in older adulthood: the moderating role of pain.
| العنوان: | Effect of depression treatment on depressive symptoms in older adulthood: the moderating role of pain. |
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| المؤلفون: | Mavandadi S; Section of Geriatric Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA. smavanda@mail.med.upenn.edu, Ten Have TR, Katz IR, Durai UN, Krahn DD, Llorente MD, Kirchner JE, Olsen EJ, Van Stone WW, Cooley SL, Oslin DW |
| المصدر: | Journal of the American Geriatrics Society [J Am Geriatr Soc] 2007 Feb; Vol. 55 (2), pp. 202-11. |
| نوع المنشور: | Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 7503062 Publication Model: Print Cited Medium: Print ISSN: 0002-8614 (Print) Linking ISSN: 00028614 NLM ISO Abbreviation: J Am Geriatr Soc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Malden, MA : Blackwell Science Original Publication: New York [etc.] |
| مواضيع طبية MeSH: | Activities of Daily Living* , Work*, Depressive Disorder/*therapy , Pain/*psychology, Aged ; Analysis of Variance ; Depression/psychology ; Depressive Disorder/etiology ; Depressive Disorder/psychology ; Humans ; Mental Health Services ; Middle Aged ; Pain Measurement ; Primary Health Care ; Referral and Consultation |
| مستخلص: | Objectives: To investigate whether pain severity and interference with normal work activities moderate the effects of depression treatment on changes in depressive symptoms over time in older adults in primary care. Design: Patient-randomized, clinical trial. Setting: Multisite: three clinics located in Veterans Affairs Medical Centers. Participants: Adults aged 60 and older (n=524) who screened positive for depression and participated in the Primary Care Research in Substance Abuse and Mental Health for the Elderly Study. Intervention: Integrated care versus enhanced specialty referral care. Measurements: Pain severity, the degree to which pain interferes with work inside and outside of the home, and depressive symptoms were examined at baseline and 3, 6, and 12 months. Results: Intention-to-treat analyses revealed that both treatment groups showed reduced depressive symptoms over time, although self-reported pain moderated reductions in depressive symptoms. At higher levels of pain severity and interference with work activities, improvements in depressive symptoms were blunted. Furthermore, pain interference appeared to have a greater effect on depressive symptoms than did pain severity; in individuals with major depression, pain interference fully accounted for the moderating effects of pain severity on changes in depressive symptoms over time. Conclusion: Pain and its interference with functioning interfere with recovery from depression. Findings highlight the importance of addressing multiple domains of functioning (e.g., physical and social disability) and the degree to which pain and other forms of physical comorbidity may hinder or minimize treatment-related improvements in depressive symptoms. |
| تواريخ الأحداث: | Date Created: 20070217 Date Completed: 20070330 Latest Revision: 20080310 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1111/j.1532-5415.2007.01042.x |
| PMID: | 17302656 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0002-8614 |
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| DOI: | 10.1111/j.1532-5415.2007.01042.x |