دورية أكاديمية
أعرض في EDS

Zinc and copper metabolism in pregnancy and lactation of adolescent women.

التفاصيل البيبلوغرافية
العنوان: Zinc and copper metabolism in pregnancy and lactation of adolescent women.
المؤلفون: Maia PA; Laboratório de Bioquímica Nutricional e de Alimentos, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Figueiredo RC, Anastácio AS, Porto da Silveira CL, Donangelo CM
المصدر: Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2007 Mar; Vol. 23 (3), pp. 248-53. Date of Electronic Publication: 2007 Feb 22.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8802712 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0899-9007 (Print) Linking ISSN: 08999007 NLM ISO Abbreviation: Nutrition Subsets: MEDLINE
أسماء مطبوعة: Publication: Tarrytown, NY : Elsevier Science
Original Publication: [Burbank, Calif. : Nutrition, c1987-
مواضيع طبية MeSH: Adolescent Nutritional Physiological Phenomena* , Nutritional Status*, Copper/*metabolism , Lactation/*metabolism , Pregnancy in Adolescence/*metabolism , Zinc/*metabolism, Adolescent ; Case-Control Studies ; Copper/deficiency ; Female ; Humans ; Nutrition Disorders/epidemiology ; Nutrition Disorders/metabolism ; Nutritional Requirements ; Pregnancy ; Zinc/deficiency
مستخلص: Objective: Pregnant and lactating adolescent women are at risk of zinc and copper deficiency but their capacity for metabolic adaptation is poorly known. This study investigated the effect of pregnancy and lactation on zinc and copper metabolism in adolescent women by comparing biochemical indices between groups in different reproductive states.
Methods: Habitual dietary intake and biochemical indices (zinc, copper, alkaline phosphatase, and ceruloplasmin in plasma; zinc [E-Zn], metallothionein [E-MT], and superoxide dismutase [E-SOD] in erythrocytes) and their relation were compared among non-pregnant non-lactating adolescents (NPNLs; n = 26), third-trimester pregnant adolescents (PAs; n = 26), and lactating adolescents up to 3 mo postpartum (LAs; n = 21).
Results: Zinc and copper intakes were not different across groups (on average, 8.7 and 1.0 mg/d, respectively). PAs had lower plasma zinc but higher plasma copper, alkaline phosphatase, and ceruloplasmin levels than did LAs and NPNLs (P < 0.05). E-SOD and E-Zn were similar in all groups but E-MT was higher in the PA and LA groups than in the NPNL group (P < 0.05). Correlations between plasma copper and ceruloplasmin and between E-MT and E-Zn were observed in the LA and NPNL groups (r > or = 0.64, P < 0.01) but not in the PA group. In contrast, correlations between plasma alkaline phosphatase and plasma zinc, between E-MT and plasma zinc, and between E-SOD and E-Zn were observed only in the PA group (r > or = 0.46, P < 0.05).
Conclusion: Zinc and copper biochemical responses to pregnancy and lactation in the adolescent women studied appeared qualitatively similar to those described in previous studies in adult women. However, the significant correlations observed between the activity of zinc-dependent enzymes and plasma (or erythrocyte) zinc suggest that a poor maternal zinc status may limit the metabolic adaptation capacity of these adolescent women especially during pregnancy.
المشرفين على المادة: 789U1901C5 (Copper)
J41CSQ7QDS (Zinc)
تواريخ الأحداث: Date Created: 20070227 Date Completed: 20070529 Latest Revision: 20131121
رمز التحديث: 20221213
DOI: 10.1016/j.nut.2007.01.003
PMID: 17320352
قاعدة البيانات: MEDLINE
الوصف
تدمد:0899-9007
DOI:10.1016/j.nut.2007.01.003