دورية أكاديمية

[Use of antagonistic Bacillus subtilis bacteria for treatment of nosocomial urinary tract infections].

التفاصيل البيبلوغرافية
العنوان: [Use of antagonistic Bacillus subtilis bacteria for treatment of nosocomial urinary tract infections].
المؤلفون: Pushkarev AM, Tuĭgunova VG, Zaĭnullin RR, Kuznetsova TN, Gabidullin IuZ
المصدر: Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2007 Mar-Apr (2), pp. 90-3.
نوع المنشور: Clinical Trial; English Abstract; Journal Article
اللغة: Russian
بيانات الدورية: Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0415217 Publication Model: Print Cited Medium: Print ISSN: 0372-9311 (Print) Linking ISSN: 03729311 NLM ISO Abbreviation: Zh Mikrobiol Epidemiol Immunobiol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2018, no. 4 (ii︠u︡lʹ-avgust)- >: Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora
Original Publication: Moskva : Izd-vo "Medit︠s︡ina"
مواضيع طبية MeSH: Bacillus subtilis*/physiology, Cross Infection/*therapy , Probiotics/*therapeutic use , Urinary Tract Infections/*therapy, Administration, Intravesical ; Administration, Oral ; Antibiosis ; Bacteria/drug effects ; Bacteria/isolation & purification ; Cross Infection/microbiology ; Culture Media, Conditioned/pharmacology ; Humans ; Microbial Sensitivity Tests ; Probiotics/administration & dosage ; Probiotics/pharmacology ; Treatment Outcome ; Urinary Tract Infections/microbiology
مستخلص: Effect of Bactisporin--a probiotic, containing spores of aerobic Bacillus subtilis 3H bacterium--for complex treatment of patients with nosocomial urinary tract infections was studied. 68 Cultures of different species of conditionally pathogenic bacteria were isolated from urine of the patients. Susceptibility of the isolated cultures to antibiotics before and after application of B. subtilis 3H metabolites was determined. The metabolites were accumulated on potato-glucose agar (PGA) while bacterium was cultivated on kapron membranes placed on surface of the medium. Influence of obtained metabolites on isolated strains was assessed by cultivation of each strain in metabolites-rich PGA during 24 h. Metabolites of B. subtilis led to decrease in resistance of isolated uropathogenic microflora to antibiotics. Use of Bactisporin in complex treatment of nosocomial urinary tract infections resulted in accelerated elimination of causative microorganism.
المشرفين على المادة: 0 (Culture Media, Conditioned)
تواريخ الأحداث: Date Created: 20070526 Date Completed: 20070622 Latest Revision: 20200716
رمز التحديث: 20221213
PMID: 17523489
قاعدة البيانات: MEDLINE