دورية أكاديمية
[Proinflammatory cytokines in children with acute enteric infections caused by enterobacteria].
| العنوان: | [Proinflammatory cytokines in children with acute enteric infections caused by enterobacteria]. |
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| المؤلفون: | Zherebtsova Ni, Valishin DA, Mavziutov AR |
| المصدر: | Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2007 May-Jun (3), pp. 48-52. |
| نوع المنشور: | English Abstract; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Country of Publication: Russia (Federation) NLM ID: 0415217 Publication Model: Print Cited Medium: Print ISSN: 0372-9311 (Print) Linking ISSN: 03729311 NLM ISO Abbreviation: Zh Mikrobiol Epidemiol Immunobiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2018, no. 4 (ii︠u︡lʹ-avgust)- >: Moskva : FBUN T︠S︡NII Ėpidemiologii Rospotrebnadzora Original Publication: Moskva : Izd-vo "Medit︠s︡ina" |
| مواضيع طبية MeSH: | Dysentery, Bacillary/*blood , Dysentery, Bacillary/*pathology , Enterobacteriaceae/*immunology , Interleukin-1beta/*blood , Interleukin-6/*blood , Tumor Necrosis Factor-alpha/*blood , Tumor Necrosis Factor-alpha/*metabolism, Adolescent ; Blood Sedimentation ; Child ; Child, Preschool ; Diarrhea/pathology ; Dysentery, Bacillary/microbiology ; Fever/pathology ; Fluorescent Antibody Technique ; Humans ; Leukocyte Count ; Leukocytosis/pathology ; Time Factors |
| مستخلص: | The levels of the proinflammatory cytokines including interleukin-1beta (IL-1beta), interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-alpha) was investigated in 73 children in the age range from 3 to 17 years with slight and medium-heavy diarrheal illness caused by pathogenic and conditionally pathogenic entrobacteria. Strong positive correlation was found between: the levels of IL-1beta, TNF-alpha and intoxication rate (r=0.65 and r=0.49); height of temperature and duration of fever (r=0.86 and r=0.66); dyspepsia (r=0.48 and r=0.41); diarrhea (r=0.37 and r=0.54) and changes in blood including number of leucocytes (r=0.40 and r=0.52) and level of erythrocyte sedimentation rate (ESR) (r=0.65 and r=0.52). Medium positive relationship between the level of IL-6 and intoxication rate (r=0.40 and r=0.52), height of temperature and duration of fever (r=0.45), changes in blood including ESR (r=0.42) and number of leucocytes (r=0.46) was shown. There was a strong positive correlation between IL-1beta and TNF-alpha (r=0.74), between IL-6 and TNF-alpha (r=0.71) and a medium positive correlation between IL-1beta and IL-6 (r=0.61). Considerable decrease in concentration of all cytokines during early period of convalescent at disease with no complications was revealed. Change in concentration of IL-1beta and TNF-alpha determines both intoxication rate and fever. High level of IL-6 is related with complications and lingering course of disease. |
| المشرفين على المادة: | 0 (Interleukin-1beta) 0 (Interleukin-6) 0 (Tumor Necrosis Factor-alpha) |
| تواريخ الأحداث: | Date Created: 20070804 Date Completed: 20070911 Latest Revision: 20200716 |
| رمز التحديث: | 20221213 |
| PMID: | 17672131 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0372-9311 |
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