دورية أكاديمية
[Treatment of painful bony metastases with Samarium 153-EDTMP in prostate carcinoma].
| العنوان: | [Treatment of painful bony metastases with Samarium 153-EDTMP in prostate carcinoma]. |
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| عنوان ترانسليتريتد: | Traitement des metastases osseuses douloureuses par le Samarium 153-EDTMP dans le cancer de la prostate. |
| المؤلفون: | Mhiri A; Service de Médecine Nucléaire, Institut Salah Azaïez, Tunis., Hassad R, Sellem A, Bahri H, Diakite R, Slim I, Mahersi M, Hammami H, Ben Adallah M, Ben Slimene MF |
| المصدر: | La Tunisie medicale [Tunis Med] 2007 Jul; Vol. 85 (7), pp. 580-5. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | French |
| بيانات الدورية: | Publisher: Societe Tunisienne Des Sciences Medicales Country of Publication: Tunisia NLM ID: 0413766 Publication Model: Print Cited Medium: Print ISSN: 0041-4131 (Print) Linking ISSN: 00414131 NLM ISO Abbreviation: Tunis Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tunis : Societe Tunisienne Des Sciences Medicales |
| مواضيع طبية MeSH: | Analgesics, Non-Narcotic/*therapeutic use , Bone Neoplasms/*radiotherapy , Organometallic Compounds/*therapeutic use , Organophosphorus Compounds/*therapeutic use , Pain, Intractable/*radiotherapy , Prostatic Neoplasms/*pathology, Aged ; Aged, 80 and over ; Bone Neoplasms/secondary ; Humans ; Male ; Middle Aged ; Radioisotopes/therapeutic use ; Retrospective Studies |
| مستخلص: | Unlabelled: THE OBJECTIVE of this work is to evaluate a new therapy, the metabolic radiotherapy to the 153Samarium-EDTMP, of recent introduction in Tunisia, in the painful bony metastasis treatment observed at the patients affected of cancer of the prostate. Methods: It is about a retrospective survey with a receding of 40 months, achieved through 45 files of patients having benefited all of this new treatment for painful bony metastases in relation with a prostatic adenocarcinoma and collected by three centers of Nuclear Medicine of the capital: the institute Salah Azaiez (state-controlled), the Center CERU (deprives) and the Military hospital (HMPIT). Results: We tried to appreciate essentially four parameters: the therapeutic efficiency, the factors influencing the answer in the treatment, the toxicity of the treatment and the sources of failure. We observed a positive answer in 92,1% of the cases, this answer was complete in 36,5% of the cases. The results gotten after multiple administrations show that the cures could be repeated with results comparable to those of the first cure. The therapeutic efficiency is at least equivalent to those of the other therapeutic means, with nearly non-existent secondary effects. The only toxicity is of hematological order; it is the most often moderate and reversible with a complete recuperation at the end of 8 weeks. Besides, the effect on the pain came with an improvement of the quality of life of the patients treaties. Conclusion: Its precocious introduction in the taken in charge of the metastatic patients, would allow them to benefit better from its efficiency, simplicity and weak toxicity and therefore to enjoy a better quality of life. |
| المشرفين على المادة: | 0 (Analgesics, Non-Narcotic) 0 (Organometallic Compounds) 0 (Organophosphorus Compounds) 0 (Radioisotopes) 745X144DZY (samarium Sm-153 lexidronam) |
| تواريخ الأحداث: | Date Created: 20071211 Date Completed: 20080124 Latest Revision: 20161124 |
| رمز التحديث: | 20240628 |
| PMID: | 18064991 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0041-4131 |
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