دورية أكاديمية
Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage.
| العنوان: | Changes of vasoactive polypeptides during postoperative hypertensive crisis in patients with hypertensive intracerebral hemorrhage. |
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| المؤلفون: | Wang Z; Department of Neurosurgery, Fourth Affiliated Hospital of Harbin Medical University, Harbin, China. wangzhi992001@yahoo.com.cn, Wang XF, Wang C, Luan WZ |
| المصدر: | Chinese medical journal [Chin Med J (Engl)] 2007 Dec 05; Vol. 120 (23), pp. 2129-31. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Chinese Medical Association ; produced by Wolters Kluwer Country of Publication: China NLM ID: 7513795 Publication Model: Print Cited Medium: Print ISSN: 0366-6999 (Print) Linking ISSN: 03666999 NLM ISO Abbreviation: Chin Med J (Engl) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2015- > : Beijing : Chinese Medical Association ; produced by Wolters Kluwer Original Publication: Peking, Chinese Medical Assn. |
| مواضيع طبية MeSH: | Hypertension/*blood , Intracranial Hemorrhage, Hypertensive/*surgery , Postoperative Complications/*blood, 6-Ketoprostaglandin F1 alpha/blood ; Adult ; Aged ; Endothelins/blood ; Female ; Humans ; Hypertension/etiology ; Intracranial Hemorrhage, Hypertensive/blood ; Intracranial Hemorrhage, Hypertensive/physiopathology ; Male ; Middle Aged ; Thromboxane B2/blood |
| مستخلص: | Background: Hypertensive crisis could be found after operation in patients with hypertensive intracerebral hemorrhage (HICH). The aim of this study was to explore the changes and the roles of some vasoactive polypeptides during postoperative hypertensive crisis in patients with HICH. Methods: A total of 31 patients, who were admitted for craniotomy, were enrolled into this study. After the operation, the patients were divided into three groups. Group I consisted of 9 patients with postoperative hypertensive crisis, and group II was composed of 13 patients without postoperative hypertensive crisis. Nine patients, who denied history of hypertension or HICH, were set as group III. The levels of some vasoactivators in the three groups were measured before and after the operation. The differences in the results among the groups were analyzed using the ANOVA. The data collected before and after the operation in the group I was compared by Wilcoxon test. Results: The concentration of endothelin in group I was significantly higher than that in group III (P < 0.05). The level of thromboxane A2 and the ratio of thromboxane B2 to 6-keto-PGF1a in group I were significantly higher than those in the other two groups (P < 0.05). In group I, the levels of plasma renin activity, angiotensin II, aldosterone, catecholamine, and endothelin before the operation were significantly higher than those determined after the operation (P > 0.05). Conclusions: Postoperative hypertensive crisis may be due to the increased thromboxane A2 and relatively inadequate prostacyclin, especially 6-keto-PGF1a. The increased level of endothelin and intraoperative stimulation also play a certain role in the development of postoperative hypertensive crisis. |
| المشرفين على المادة: | 0 (Endothelins) 54397-85-2 (Thromboxane B2) 58962-34-8 (6-Ketoprostaglandin F1 alpha) |
| تواريخ الأحداث: | Date Created: 20080103 Date Completed: 20080205 Latest Revision: 20080102 |
| رمز التحديث: | 20240628 |
| PMID: | 18167188 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0366-6999 |
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