دورية أكاديمية
Babesiosis: recent insights into an ancient disease.
العنوان: | Babesiosis: recent insights into an ancient disease. |
---|---|
المؤلفون: | Hunfeld KP; Institute of Medical Microbiology & Infection Control, Hospital of the Johann Wolfgang Goethe-University Frankfurt am Main, Department of Serology and Molecular Diagnostics, Frankfurt/Main, Germany. K.Hunfeld@em.uni-frankfurt.de, Hildebrandt A, Gray JS |
المصدر: | International journal for parasitology [Int J Parasitol] 2008 Sep; Vol. 38 (11), pp. 1219-37. Date of Electronic Publication: 2008 Mar 20. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 0314024 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0020-7519 (Print) Linking ISSN: 00207519 NLM ISO Abbreviation: Int J Parasitol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Oxford : Elsevier Science Original Publication: Oxford, New York, Pergamon Press. |
مواضيع طبية MeSH: | Babesiosis*/diagnosis , Babesiosis*/drug therapy , Babesiosis*/transmission , Communicable Diseases, Emerging*/diagnosis , Communicable Diseases, Emerging*/drug therapy , Communicable Diseases, Emerging*/parasitology , Communicable Diseases, Emerging*/transmission , Zoonoses*/parasitology , Zoonoses*/transmission, Disease Reservoirs/*parasitology, Animals ; Animals, Domestic/parasitology ; Animals, Wild/parasitology ; Babesia/classification ; Babesia/physiology ; Cattle ; Disease Vectors ; Dogs ; Fluorescent Antibody Technique, Indirect ; Host-Parasite Interactions ; Humans ; North America ; Phylogeny ; Prevalence ; Ticks ; Transfusion Reaction |
مستخلص: | Ever since the discovery of parasitic inclusions in erythrocytes of cattle in Romania by Victor Babes at the end of the 19th century, newly recognised babesial pathogens continue to emerge around the world and the substantial public health impact of babesiosis on livestock and man is ongoing. Babesia are transmitted by ixodid ticks and infection of the host causes a host-mediated pathology and erythrocyte lysis, resulting in anemia, hyperbilirubinuria, hemoglobinuria, and possibly organ failure. Recently obtained molecular data, particularly for the 18S rRNA gene, has contributed significantly to a better understanding of the sometimes puzzling phylogenetic situation of the genus Babesia and new information has been added to help determine the taxonomic position of many species. Moreover, it seems that owing to higher medical awareness the number of reported cases in humans is rising steadily. Hitherto unknown zoonotic babesias are now being reported from geographical areas where babesiosis was not known to occur and the growing numbers of immunocompromised individuals suggest that the frequency of cases will continue to rise. This review covers recent insights into human babesiosis with regard to phylogeny, diagnostics and treatment in order to provide new information on well known as well as recently discovered parasites with zoonotic potential. |
Number of References: | 37 |
تواريخ الأحداث: | Date Created: 20080429 Date Completed: 20090618 Latest Revision: 20220309 |
رمز التحديث: | 20221213 |
DOI: | 10.1016/j.ijpara.2008.03.001 |
PMID: | 18440005 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0020-7519 |
---|---|
DOI: | 10.1016/j.ijpara.2008.03.001 |