دورية أكاديمية
Does endoscopic retrograde cholangiopancreatography reduce the risk of local pancreatic complications in acute pancreatitis? A systematic review and metaanalysis.
العنوان: | Does endoscopic retrograde cholangiopancreatography reduce the risk of local pancreatic complications in acute pancreatitis? A systematic review and metaanalysis. |
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المؤلفون: | Petrov MS; Department of Surgery, Nizhny Novgorod State Medical Academy, PO Box 568, Nizhny Novgorod, 603000, Russia. max.petrov@gmail.com, Uchugina AF, Kukosh MV |
المصدر: | Surgical endoscopy [Surg Endosc] 2008 Nov; Vol. 22 (11), pp. 2338-43. Date of Electronic Publication: 2008 Jun 05. |
نوع المنشور: | Journal Article; Meta-Analysis; Review; Systematic Review |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Country of Publication: Germany NLM ID: 8806653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2218 (Electronic) Linking ISSN: 09302794 NLM ISO Abbreviation: Surg Endosc Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 1992- : New York : Springer Original Publication: [Berlin] : Springer International, c1987- |
مواضيع طبية MeSH: | Cholangiopancreatography, Endoscopic Retrograde*, Pancreatitis/*complications , Pancreatitis/*diagnostic imaging , Pancreatitis/*surgery , Postoperative Complications/*prevention & control, Humans ; Randomized Controlled Trials as Topic ; Risk |
مستخلص: | Background: Recent studies have added to the controversy regarding the role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of patients with acute biliary pancreatitis. This debate is due in part to a marked difference between the trials regarding the definition of "complication" as an outcome. This study sought to determine the effect of early ERCP versus conservative treatment on local pancreatic complications (defined by the current classification) experienced by patients with acute biliary pancreatitis. Methods: Electronic databases (Cochrane Central Register of Controlled Trials, MEDLINE, Science Citation Index) and conference proceedings were searched for relevant randomized controlled trials up to December 2007. The effect of both treatment strategies on local pancreatic complications was calculated with random-effects models. Results: Five trials involving 717 patients were included in this systematic review. Pooled analysis of all the patients with acute pancreatitis did not demonstrate a statistically significant difference between the two treatment strategies (relative risk [RR], 0.94; 95% confidence interval [CI], 0.63-1.40; p = 0.62). Similar results were observed after subgroup analysis based on the severity of disease as follows: mild acute pancreatitis (RR, 0.79; 95% CI, 0.26-2.47; p = 0.69); severe acute pancreatitis (RR, 0.77; 95% CI, 0.30-1.98; p = 0.59). Conclusion: The early use of ERCP did not result in a significantly reduced risk of local pancreatic complications for either patients with mild acute pancreatitis or those with severe form of the disease. |
Number of References: | 29 |
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تواريخ الأحداث: | Date Created: 20080606 Date Completed: 20090113 Latest Revision: 20211020 |
رمز التحديث: | 20221213 |
DOI: | 10.1007/s00464-008-9964-2 |
PMID: | 18528624 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1432-2218 |
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DOI: | 10.1007/s00464-008-9964-2 |