دورية أكاديمية
أعرض في EDS

Does endoscopic retrograde cholangiopancreatography reduce the risk of local pancreatic complications in acute pancreatitis? A systematic review and metaanalysis.

التفاصيل البيبلوغرافية
العنوان: Does endoscopic retrograde cholangiopancreatography reduce the risk of local pancreatic complications in acute pancreatitis? A systematic review and metaanalysis.
المؤلفون: Petrov MS; Department of Surgery, Nizhny Novgorod State Medical Academy, PO Box 568, Nizhny Novgorod, 603000, Russia. max.petrov@gmail.com, Uchugina AF, Kukosh MV
المصدر: Surgical endoscopy [Surg Endosc] 2008 Nov; Vol. 22 (11), pp. 2338-43. Date of Electronic Publication: 2008 Jun 05.
نوع المنشور: Journal Article; Meta-Analysis; Review; Systematic Review
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 8806653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2218 (Electronic) Linking ISSN: 09302794 NLM ISO Abbreviation: Surg Endosc Subsets: MEDLINE
أسماء مطبوعة: Publication: 1992- : New York : Springer
Original Publication: [Berlin] : Springer International, c1987-
مواضيع طبية MeSH: Cholangiopancreatography, Endoscopic Retrograde*, Pancreatitis/*complications , Pancreatitis/*diagnostic imaging , Pancreatitis/*surgery , Postoperative Complications/*prevention & control, Humans ; Randomized Controlled Trials as Topic ; Risk
مستخلص: Background: Recent studies have added to the controversy regarding the role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of patients with acute biliary pancreatitis. This debate is due in part to a marked difference between the trials regarding the definition of "complication" as an outcome. This study sought to determine the effect of early ERCP versus conservative treatment on local pancreatic complications (defined by the current classification) experienced by patients with acute biliary pancreatitis.
Methods: Electronic databases (Cochrane Central Register of Controlled Trials, MEDLINE, Science Citation Index) and conference proceedings were searched for relevant randomized controlled trials up to December 2007. The effect of both treatment strategies on local pancreatic complications was calculated with random-effects models.
Results: Five trials involving 717 patients were included in this systematic review. Pooled analysis of all the patients with acute pancreatitis did not demonstrate a statistically significant difference between the two treatment strategies (relative risk [RR], 0.94; 95% confidence interval [CI], 0.63-1.40; p = 0.62). Similar results were observed after subgroup analysis based on the severity of disease as follows: mild acute pancreatitis (RR, 0.79; 95% CI, 0.26-2.47; p = 0.69); severe acute pancreatitis (RR, 0.77; 95% CI, 0.30-1.98; p = 0.59).
Conclusion: The early use of ERCP did not result in a significantly reduced risk of local pancreatic complications for either patients with mild acute pancreatitis or those with severe form of the disease.
Number of References: 29
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تواريخ الأحداث: Date Created: 20080606 Date Completed: 20090113 Latest Revision: 20211020
رمز التحديث: 20221213
DOI: 10.1007/s00464-008-9964-2
PMID: 18528624
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-2218
DOI:10.1007/s00464-008-9964-2