دورية أكاديمية
Incidence of ipsilateral postoperative deep venous thrombosis in the amputated lower extremity of patients with peripheral obstructive arterial disease.
| العنوان: | Incidence of ipsilateral postoperative deep venous thrombosis in the amputated lower extremity of patients with peripheral obstructive arterial disease. |
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| المؤلفون: | Matielo MF; Division of Vascular and Endovascular Surgery, Clinics Hospital of the Faculty of Medicine, São Paulo University, São Paulo, Brazil. mmatielo@uninet.com.br, Presti C, Casella IB, Netto BM, Puech-Leão P |
| المصدر: | Journal of vascular surgery [J Vasc Surg] 2008 Dec; Vol. 48 (6), pp. 1514-9. Date of Electronic Publication: 2008 Oct 01. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 8407742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6809 (Electronic) Linking ISSN: 07415214 NLM ISO Abbreviation: J Vasc Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2008-> : New York, NY : Elsevier Original Publication: St. Louis, Mo. : Mosby, [c1984- |
| مواضيع طبية MeSH: | Femoral Vein*, Amputation, Surgical/*adverse effects , Arterial Occlusive Diseases/*surgery , Venous Thrombosis/*epidemiology, Adult ; Aged ; Aged, 80 and over ; Brazil/epidemiology ; Female ; Follow-Up Studies ; Humans ; Incidence ; Leg/surgery ; Male ; Middle Aged ; Postoperative Complications ; Prospective Studies ; Risk Factors ; Ultrasonography, Doppler, Color ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/etiology |
| مستخلص: | Objective: Patients undergoing amputation of the lower limb due to peripheral arterial disease (PAD) are at risk of developing deep venous thrombosis (DVT). Few studies in the research literature report the incidence of DVT during the early postoperative period or the risk factors for the development of DVT in the amputation stump. This prospective study evaluated the incidence of DVT during the first 35 postoperative days in patients who had undergone amputation of the lower extremity due to PAD and its relation to comorbidities and death. Methods: Between September 2004 and March 2006, 56 patients (29 men), with a mean age of 67.25 years, underwent 62 amputations, comprising 36 below knee amputations (BKA) and 26 above knee amputations (AKA). Echo-Doppler scanning was performed preoperatively and on postoperative days 7 and 31 (approximately). All patients received acetylsalicylic acid (100 mg daily) preoperatively and postoperatively, but none received prophylactic anticoagulation. Results: DVT occurred in 25.8% of extremities with amputations (10 AKA and 6 BKA). The cumulative incidence in the 35-day postoperative period was 28% (Kaplan-Meier). There was a significant difference (P = .04) in the incidence of DVT between AKA (37.5%) and BKA (21.2%). Age >or=70 years (48.9% vs 16.8%, P = .021) was also a risk factor for DVT in the univariate analysis. Of the 16 cases, 14 (87.5%) were diagnosed during outpatient care. The time to discharge after amputation was averaged 6.11 days in-hospital stay (range, 1-56 days). One symptomatic nonfatal pulmonary embolism occurred in a patient already diagnosed with DVT. There was no relation between other comorbidities and DVT. The multivariate analysis showed no association between risk factors and the occurrence of DVT in the amputated extremity. DVT ipsilateral to the amputation did not influence the mortality rate (9.7%). Conclusion: The incidence of DVT in the early postoperative period ( |
| تواريخ الأحداث: | Date Created: 20081003 Date Completed: 20090122 Latest Revision: 20221207 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1016/j.jvs.2008.07.055 |
| PMID: | 18829221 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1097-6809 |
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| DOI: | 10.1016/j.jvs.2008.07.055 |