دورية أكاديمية

Evaluation of patients with symptoms suggestive of chronic polyneuropathy.

التفاصيل البيبلوغرافية
العنوان: Evaluation of patients with symptoms suggestive of chronic polyneuropathy.
المؤلفون: Johannsen L; From the Departments of *Neurology and daggerPathology, Odense University Hospital, Odense, Denmark., Smith T, Havsager AM, Madsen C, Kjeldsen MJ, Dalsgaard NJ, Gaist D, Schrøder HD, Sindrup SH
المصدر: Journal of clinical neuromuscular disease [J Clin Neuromuscul Dis] 2001 Dec; Vol. 3 (2), pp. 47-52.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100887391 Publication Model: Print Cited Medium: Internet ISSN: 1537-1611 (Electronic) Linking ISSN: 15220443 NLM ISO Abbreviation: J Clin Neuromuscul Dis Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Hagerstown, MD : Lippincott Williams & Wilkins, c1999-
مستخلص: Objectives: The aim of this study was to determine the diagnostic yield and to describe the spectrum of diagnosis encountered by evaluation of patients with symptoms suggestive of chronic polyneuropathy.
Methods: We prospectively evaluated 198 patients referred to a department of neurology with symptoms suggestive of polyneuropathy. The evaluation included nerve conduction studies with near-nerve technique, quantitative examination of temperature sensation, blood tests, chest x-rays, and skin biopsies as well as diagnostic tests for differential diagnoses.
Results: Polyneuropathy was found in 147 patients, alternative diagnoses in 25, and 26 remained undiagnosed. The etiology of polyneuropathy could not be identified in 25% of the patients with polyneuropathy. In the remaining 75%, the cause of neuropathy was diabetes and/or alcohol abuse (41%), monoclonal gammopathy of undetermined significance (5%), drugs (5%), connective tissue disease (3%), and a number of less frequent conditions. A previously undiagnosed condition was found in 30% of the patients with polyneuropathy.
Conclusion: Evaluation of patients with symptoms suggestive of polyneuropathy reveals a high fraction of patients with previously undiagnosed conditions both in patients ending up with a polyneuropathy diagnosis and those without this diagnosis.
تواريخ الأحداث: Date Created: 20081217 Date Completed: 20121002 Latest Revision: 20220317
رمز التحديث: 20240628
DOI: 10.1097/00131402-200112000-00001
PMID: 19078654
قاعدة البيانات: MEDLINE
الوصف
تدمد:1537-1611
DOI:10.1097/00131402-200112000-00001