دورية أكاديمية
[Age-related macular degeneration (AMD)].
العنوان: | [Age-related macular degeneration (AMD)]. |
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عنوان ترانسليتريتد: | Altersbezogene Makuladegeneration (AMD). |
المؤلفون: | Michels S; Augenklinik, Universitätsspital Zürich. stephan.michels@usz.ch, Kurz-Levin M |
المصدر: | Therapeutische Umschau. Revue therapeutique [Ther Umsch] 2009 Mar; Vol. 66 (3), pp. 189-95. |
نوع المنشور: | Journal Article; Review |
اللغة: | German |
بيانات الدورية: | Publisher: Aerzteverlag medinfo AG Country of Publication: Switzerland NLM ID: 0407224 Publication Model: Print Cited Medium: Print ISSN: 0040-5930 (Print) Linking ISSN: 00405930 NLM ISO Abbreviation: Ther Umsch Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2023- : Erlenbach : Aerzteverlag medinfo AG Original Publication: Bern, Huber. |
مواضيع طبية MeSH: | Macular Degeneration*/diagnosis , Macular Degeneration*/drug therapy , Macular Degeneration*/epidemiology , Macular Degeneration*/etiology , Macular Degeneration*/genetics , Macular Degeneration*/prevention & control, Adult ; Age Factors ; Aged ; Antioxidants/therapeutic use ; Aptamers, Nucleotide/therapeutic use ; Diet ; Fluorescein Angiography ; Fundus Oculi ; Genetic Predisposition to Disease ; Humans ; Middle Aged ; Photochemotherapy ; Polymorphism, Genetic ; Prevalence ; Prospective Studies ; Randomized Controlled Trials as Topic ; Risk Factors ; Smoking/adverse effects ; Tomography, Optical Coherence ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Visual Acuity ; Zinc/therapeutic use |
مستخلص: | Today age-related macular degeneration (AMD) is the most frequent cause for legal blindness in western industrialized countries. The prevalence of this disease rises with increasing age. A multifactorial pathogenesis of AMD is postulated including genetic predisposition and environmental risk factors. The most relevant modifiable risk factor is smoking. Up to today there is no cure of this chronic disease. Prophylaxis, including a healthy diet and antioxidants as nutrional supplements for selected patients, aims to slow down the disease progression. Significant progress has been made in the treatment of the neovascular form of the disease using inhibitors of the vascular endothelial growth factor (VEGF). |
Number of References: | 14 |
المشرفين على المادة: | 0 (Antioxidants) 0 (Aptamers, Nucleotide) 0 (Vascular Endothelial Growth Factor A) 2H1PA8H1EN (pegaptanib) J41CSQ7QDS (Zinc) |
تواريخ الأحداث: | Date Created: 20090307 Date Completed: 20090515 Latest Revision: 20161125 |
رمز التحديث: | 20240628 |
DOI: | 10.1024/0040-5930.66.3.189 |
PMID: | 19266466 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0040-5930 |
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DOI: | 10.1024/0040-5930.66.3.189 |