دورية أكاديمية
[Induced pluripotent stem cells].
| العنوان: | [Induced pluripotent stem cells]. |
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| المؤلفون: | Shevchenko AI, Medvedev SP, Mazurok NA, Zakiian SM |
| المصدر: | Genetika [Genetika] 2009 Feb; Vol. 45 (2), pp. 160-8. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0047354 Publication Model: Print Cited Medium: Print ISSN: 0016-6758 (Print) Linking ISSN: 00166758 NLM ISO Abbreviation: Genetika Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Moskva : Izdatelstvo Nauka |
| مواضيع طبية MeSH: | Cell Dedifferentiation*, Pluripotent Stem Cells/*metabolism , Transcription Factors/*metabolism, Animals ; Genetic Vectors ; Humans ; Kruppel-Like Factor 4 ; Pluripotent Stem Cells/cytology ; Transcription Factors/genetics ; Transduction, Genetic ; Viruses |
| مستخلص: | Induced pluripotent stem cells (iPS) result from a reprogramming of somatic cells via transduction with viral vectors expressing the Oct4, Sox2, c-Myc, Klf4, Nanog, and Lin28 genes, which are essential for the establishment and maintenance of the pluripotent state. In properties, iPS are almost fully similar to embryonic stem cells (ESC). To date, iPS have been obtained from various differentiated cells of mice and humans. Along with ESC, iPS are highly promising for research and medicine. |
| Number of References: | 60 |
| المشرفين على المادة: | 0 (KLF4 protein, human) 0 (Klf4 protein, mouse) 0 (Kruppel-Like Factor 4) 0 (Transcription Factors) |
| تواريخ الأحداث: | Date Created: 20090402 Date Completed: 20090421 Latest Revision: 20211203 |
| رمز التحديث: | 20221213 |
| PMID: | 19334609 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0016-6758 |
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