دورية أكاديمية

[Non-parametric methods for estimating confidence intervals around the incremental cost-effectiveness ratio].

التفاصيل البيبلوغرافية
العنوان: [Non-parametric methods for estimating confidence intervals around the incremental cost-effectiveness ratio].
عنوان ترانسليتريتد: I metodi non parametrici per la stima dell'intervallo di confidenza del rapporto incrementale di costo-efficacia.
المؤلفون: Petrinco M; Dipartimento di sanità pubblica e microbiologia, Università di Torino., Gregori D, Lazzarato F, Brunello F, Veltri A, Berchialla P, Pagano E
المصدر: Epidemiologia e prevenzione [Epidemiol Prev] 2008 Nov-Dec; Vol. 32 (6), pp. 307-13.
نوع المنشور: English Abstract; Journal Article
اللغة: Italian
بيانات الدورية: Publisher: Cooperativa epidemiologia e prevenzione Country of Publication: Italy NLM ID: 8902507 Publication Model: Print Cited Medium: Print ISSN: 1120-9763 (Print) Linking ISSN: 11209763 NLM ISO Abbreviation: Epidemiol Prev Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Milano : Cooperativa epidemiologia e prevenzione
مواضيع طبية MeSH: Confidence Intervals* , Cost-Benefit Analysis* , Statistics, Nonparametric*, Carcinoma, Hepatocellular/*economics , Liver Neoplasms/*economics , Randomized Controlled Trials as Topic/*economics, Carcinoma, Hepatocellular/therapy ; Health Care Costs ; Humans ; Italy ; Liver Neoplasms/therapy ; Mathematical Computing ; Randomized Controlled Trials as Topic/statistics & numerical data
مستخلص: In recent years, cost-effectiveness analysis has become a frequent component of randomized clinical trials. In statistical terms, the major efforts addressed the method for estimating the Incremental Cost Effectiveness Ratio (ICER) and its confidence interval both with parametric and non-parametric methods. The goal of the present work is to briefly present the main non-parametric methods, based on a bootstrap approach. The methods which have been considered were applied to the data of a randomized clinical trial comparing two alternative approaches to treat hepatocellular carcinoma. The example shows that the application of different methods leads to significantly different confidence intervals' estimates, with consequences on the interpretation of the study results.
تواريخ الأحداث: Date Created: 20090410 Date Completed: 20090506 Latest Revision: 20090409
رمز التحديث: 20240628
PMID: 19353965
قاعدة البيانات: MEDLINE