دورية أكاديمية

Analysis of the bactericidal effect of ozone pneumoperitoneum.

التفاصيل البيبلوغرافية
العنوان: Analysis of the bactericidal effect of ozone pneumoperitoneum.
المؤلفون: Silva RA; Santa Casa de Sao Paulo, Faculty of Medical Sciences, Sao Paulo, Brazil. roaltenfelder@terra.com.br, Garotti JE, Silva RS, Navarini A, Pacheco AM Jr
المصدر: Acta cirurgica brasileira [Acta Cir Bras] 2009 Mar-Apr; Vol. 24 (2), pp. 124-7.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina Country of Publication: Brazil NLM ID: 9103983 Publication Model: Print Cited Medium: Internet ISSN: 1678-2674 (Electronic) Linking ISSN: 01028650 NLM ISO Abbreviation: Acta Cir Bras Subsets: MEDLINE
أسماء مطبوعة: Publication: Sao Paulo : Sociedade Brasileira Para O Desenvolvimento Da Pesquisa Em Cirurgia Curso De Pos-Graduacao Em Tecnica Operatoria E Cirurgia Experimental Escola Paulista De Medicina
Original Publication: São Paulo : A Sociedade,
مواضيع طبية MeSH: Anti-Bacterial Agents/*pharmacology , Escherichia coli/*drug effects , Ozone/*pharmacology , Peritonitis/*microbiology , Pneumoperitoneum/*microbiology, Animals ; Carbon Dioxide/pharmacology ; Peritonitis/drug therapy ; Pneumoperitoneum/drug therapy ; Rats ; Rats, Wistar ; Statistics, Nonparametric
مستخلص: Purpose: To assess the bactericidal action of ozone pneumoperitonium, and to compare the results with CO2.
Methods: It was used 36 Wistar rats. The animals, under anesthesia, were inoculated with 2ml of E. coli ATCC at a concentration of 10(10)UFC, and 1ml of BaSO4, into the peritoneal cavity. They were divided into three groups: Group 1, CO2 pneumoperitoneum was performed for 15 minutes; Group 2, ozone pneumoperitoneum was performed for 5 minutes at a concentration of 42microg/ml, and Group 3, ozone pneumoperitoneum was performed for 5 minutes at a concentration of 62microg/ml. Six animals from each group were sacrificed after the experiment, and the remaining 6 observed for 24 hours. Material was collected from the cavity of all animals for microbiological study.
Results: Ozone presented a greater bactericidal effect than CO2 in those animals sacrificed immediately after pneumoperitoneum. In the animals studied 24 hours after pneumoperitoneum evidenced no difference in bactericidal effect between the two gases. Moreover, no difference in mortality was observed.
Conclusion: Ozone has a more potent bactericidal effect than carbon dioxide gas, although this did not influence survival of the animals.
المشرفين على المادة: 0 (Anti-Bacterial Agents)
142M471B3J (Carbon Dioxide)
66H7ZZK23N (Ozone)
تواريخ الأحداث: Date Created: 20090421 Date Completed: 20091123 Latest Revision: 20191027
رمز التحديث: 20231215
DOI: 10.1590/s0102-86502009000200009
PMID: 19377781
قاعدة البيانات: MEDLINE
الوصف
تدمد:1678-2674
DOI:10.1590/s0102-86502009000200009