دورية أكاديمية
Pulsatile perfusion of kidney allografts.
| العنوان: | Pulsatile perfusion of kidney allografts. |
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| المؤلفون: | Matsuoka L; Abdominal Organ Transplantation Division, Keck School of Medicine, University of Southern California, Los Angeles, California 91101, USA. lmatsuoka@surgery.usc.edu, Almeda JL, Mateo R |
| المصدر: | Current opinion in organ transplantation [Curr Opin Organ Transplant] 2009 Aug; Vol. 14 (4), pp. 365-9. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9717388 Publication Model: Print Cited Medium: Internet ISSN: 1531-7013 (Electronic) Linking ISSN: 10872418 NLM ISO Abbreviation: Curr Opin Organ Transplant Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003->: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Philadelphia, PA : Rapid Science Publishers, |
| مواضيع طبية MeSH: | Cold Ischemia* , Organ Preservation* , Perfusion*, Kidney Transplantation/*methods, Delayed Graft Function/etiology ; Delayed Graft Function/prevention & control ; Graft Survival ; Humans ; Kidney Transplantation/adverse effects ; Pulsatile Flow ; Time Factors ; Tissue Donors/supply & distribution ; Transplantation, Homologous ; Treatment Outcome ; United States ; Waiting Lists |
| مستخلص: | Purpose of Review: The purpose of this article is to describe the current use of pulsatile kidney perfusion during organ preservation and the effects on kidney allograft outcomes and utilization. Recent Findings: As of spring 2008, there were 75 629 candidates on the kidney waiting list in the USA according to United Network for Organ Sharing data. In 2006, a total of 1815 deceased donor expanded criteria donors kidneys were transplanted, and approximately 80% of those kidneys had cold ischemic time of over 12 h. The utilization of kidney pulsatile perfusion varies extensively throughout the USA with rates of 7-12% in our institution. Summary: Data on the use of pulsatile hypothermic perfusion for kidneys during organ preservation are limited and mostly retrospective. Most authors agree that pulsatile perfusion is safe and leads to a decrease in delayed graft function, especially for marginal kidneys from extended criteria or deceased donors. The long-term effects of delayed graft function on graft survival remain to be seen. With the recent large-sampled international prospective randomized trial recently completed, we may see more kidneys pulsatile perfused. This may lead to an increase in the utilization of otherwise discarded kidneys, though these data are difficult to extrapolate. |
| Number of References: | 25 |
| تواريخ الأحداث: | Date Created: 20090718 Date Completed: 20090924 Latest Revision: 20191027 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1097/mot.0b013e32832dbd1c |
| PMID: | 19610170 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1531-7013 |
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| DOI: | 10.1097/mot.0b013e32832dbd1c |